Results 81 to 90 of about 20,465 (309)

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

The Error of Thinking that the Picture of Actual Dreams can be Used in only one Way [PDF]

, 2003
In 1914, the Spanish novelist, dramatist, poet and philosopher Miguel de Unamuno published one of his well-known works, Niebla. Unamuno allows that his characters speak and speak although they say nothing at all: in this way the author begins believing ...
Ariso, Jose Maria
core  

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

FEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca, Anna Tricarico, Martina Furfaro, Priyam Ghosh, Ennio Prosperi, Lucia Anna Stivala, Ornella Cazzalini   +6 more
wiley   +1 more source

What Can Arab Countries Learn From Post-communist Transition? [PDF]

, 2012
The commentary by Marek Dabrowski on what Arab countries can learn from the post-communist transition of the early 1990s, after the political uprisings against the authoritarian regimes in the Arab ...
Dabrowski, Marek
core  

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

Altered expression response upon repeated gene repression in single yeast cells. [PDF]

PLoS Comput Biol, 2022
Schuh L, Kukhtevich I, Bheda P, Schulz M, Bordukova M, Schneider R, Marr C.   +6 more
europepmc   +1 more source

The Situation of the Representatives of Statehood Period Elite in Soviet Lithuania: the Case of Petras Klimas

Genocidas ir Rezistencija, 2011
After Lithuania was occupied by the USSR, and lost its statehood, the cultural, political, and scientific elite who did not emigrate, or who could not conform to the new system, suffered reprisals which complicated their lives within the Soviet reality.
Vilma Bukaitė
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Bringing bodies back in: for a phenomenological and psychoanalytic film criticism of embodied cultural identity [PDF]

, 2011
This article reassesses the concept of identification in line with the increased importance phenomenology has taken on in film-philosophy of the 1990s and 2000s. In the 1970s and 1980s, a Lacanian psychoanalytic interpretation of identification dominated
Ince, Kate
core   +1 more source

Revolutionary tribunals of the Tambov province 1918–1922

Вестник Тамбовского университета. Серия: Гуманитарные науки
Importance. Reforming the public administration system is impossible without analyzing and taking into account the historical experience of the activities of punitive authorities.
S. A. Parakhin
doaj   +1 more source