Results 101 to 110 of about 5,282 (302)

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Tuskulėnai Mass Burial Grounds Occurence: 1944 or 1945?

Genocidas ir Rezistencija, 2017
The purpose of this article is to establish the date when Soviet secret police agencies started to use the territory of Tuskulėnai Manor as mass burial grounds in Vilnius.
Remigijus Černius
doaj   +1 more source

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

FEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima, Gustavo Narvaes Guimarães, Emilyane de Oliveira Santana Amaral, Bianca Caroline Figueiredo Bianco, Manuel Jara‐Espejo, Sérgio Roberto Peres Line, Ana Paula de Souza, Aline Cristiane Planello   +7 more
wiley   +1 more source

Repressions are Against the Teachers of the Sumy State Pedagogical College in 30-th of ХХ of Century [PDF]

, 2018
У статті висвітлено еволюцію ставлення радянської влади до інтелігенції, зокрема викладачів Сумського державного педагогічного інституту в 30-х роках ХХ століття.
Семешин Едуард Володимирович, Snahoshchenko Valentyna Volodymyrivna, Semeshyn Eduard Volodymyrovych, Снагощенко Валентина Володимирівна   +3 more
core   +1 more source

On some aspects of economic and legal regulation of Church property during the period of Soviet State foundation and development

Studia Humanitatis, 2020
The article analyses the regulation of property relations between religious organizations and the Soviet government. Immediately after the establishment of Soviet power all the property of religious organizations was nationalized.
Maryin Evgeniy Vladimirovich
doaj  

Altered expression response upon repeated gene repression in single yeast cells. [PDF]

PLoS Comput Biol, 2022
Schuh L, Kukhtevich I, Bheda P, Schulz M, Bordukova M, Schneider R, Marr C.   +6 more
europepmc   +1 more source

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Political Repressions in the Mongol Empire, Golden Horde and Other Turkic-Mongol States, and their Justifications (13th–16th cc.) [PDF]

, 2014
In this article the author analyses the cases of political repressions in the Mongol Empire, Golden Horde and other Turkic-Mongol states of the 13th–16th centuries.
R.Yu. Pochekaev
core   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source