Results 121 to 130 of about 20,465 (309)
Temporal and Cell‐Specific Regulation of Synaptic Homeostasis by the Chromatin Remodeler Chd1
Advanced Science, EarlyView.Chd1, the Drosophila homologue of mammalian CHD2 ‐ a gene linked to autism, epilepsy, and intellectual disability, is required for synaptic homeostatic plasticity. Chd1 in glia is necessary for the rapid induction of synaptic homeostasis, whereas Chd1 in motoneurons, muscle, and glia is critical for long‐term maintenance.
Danielle T. Morency +19 more
wiley +1 more source
RETREG1‐Mediated Reticulophagy is Essential for Dendritic Cell Maturation and Function in Sepsis
Advanced Science, EarlyView.Reticulophagy regulator 1 (RETREG1) maintains dendritic cell (DC) maturation and function in early sepsis. Mechanistically, activating transcription factor 6 (ATF6) acts as a direct transcription factor regulating RETREG1 expression in response to sepsis‐induced endoplasmic reticulum (ER) stress.
Ren‐Qi Yao +28 more
wiley +1 more source
On the Consistency between Gene Expression and the Gene Regulatory Network of Corynebacterium glutamicum. [PDF]
Netw Syst Med, 2021 Parise D +7 more
europepmc +1 more source
Політичні репресії та терор як соціально-правові феномени: кримінологічний аспект [PDF]
, 2015 Орлов, Ю. В. Політичні репресії та терор як соціально-правові феномени: кримінологічний аспект // Вісник Кримінологічної асоціації України. - 2015. - № 3 (11). - С. 167-179.Орлов Ю. В.
ORCID: http://orcid.org/0000-0003-1981-0794 +2 more
core
ERK‐Mediated Phosphorylation of YAP Defines a Noncanonical FGF Signaling Mechanism in Stem Cells
Advanced Science, EarlyView.With a powerful combination of in vivo, ex vivo, and in vitro models, the authors highlight a novel FGF‐ERK signaling regulation of YAP at the S128 site in neural crest‐derived stem cells. This study opens exciting new directions in stem cell biology and craniofacial biology, paving the way for potential innovations in the treatment of craniofacial ...
Xiaolei Zhao +16 more
wiley +1 more source
Robustness and innovation in synthetic genotype networks. [PDF]
Nat Commun, 2023 Santos-Moreno J +4 more
europepmc +1 more source
Plural: History, Culture, Society, 2014 Review on book - Igor Caşu, Duşmanul de clasă.
Petru Negura
doaj
Advanced Science, EarlyView.By integrating data from in vitro, ex vivo, and in vivo models, our research identifies the MARV glycoprotein as a remarkable hemorrhagic factor, filling a major gap in this important field. It also provides practical experimental tools for the basic research on viral pathogenesis and applied research aimed at antiviral intervention for hemorrhagic ...
Ting Yao +11 more
wiley +1 more source
Integrating heterogeneous knowledges for understanding biological behaviors: a probabilistic approach [PDF]
, 2007 Despite recent molecular technique improvements, biological knowledge remains incomplete. Reasoning on living systems hence implies to integrate heterogeneous and partial informations.
Bourdon, Jérémie +3 more
core +2 more sources
Advanced Science, EarlyView.We report a new thiolate‐reactive α,α‐gem‐dibromo lactam warhead that activates transcription factor Nrf2 and demonstrates anti‐inflammatory activities, which have implications in cancer, neurodegeneration, and cardiovascular diseases. RNA‐seq illuminated detailed transcriptional profiles, and chemical reactions with cysteine‐containing compounds ...
Beau R. Brummel +16 more
wiley +1 more source