Results 11 to 20 of about 30,544 (313)

Roles of Specialized Chromatin and DNA Structures at Subtelomeres in Schizosaccharomyces pombe

Biomolecules, 2023
Eukaryotes have linear chromosomes with domains called telomeres at both ends. The telomere DNA consists of a simple tandem repeat sequence, and multiple telomere-binding proteins including the shelterin complex maintain chromosome-end structures and ...
Junko Kanoh
doaj   +2 more sources

Structural insight into glucose repression of the mannitol operon [PDF]

Scientific Reports, 2019
AbstractCarbon catabolite repression is a regulatory mechanism to ensure sequential utilization of carbohydrates and is usually accomplished by repression of genes for the transport and metabolism of less preferred carbon compounds by a more preferred one.
Mangyu Choe, Huitae Min, Young-Ha Park, Yeon-Ran Kim, Jae-Sung Woo, Yeong-Jae Seok   +5 more
openaire   +2 more sources

Polycomb repressive complex 2 regulates sexual development in <i>Neurospora crassa</i>. [PDF]

mBio
In most branches of the fungal kingdom, sexual development marks a dramatic shift from simple multicellular hyphae to complex fruiting bodies composed of multiple tissues and cell types.
Deaven AM, Ameri-Solanky AJ, Lewis ZA.
europepmc   +2 more sources

Structure, mechanism, and regulation of polycomb-repressive complex 2 [PDF]

Journal of Biological Chemistry, 2018
Polycomb repressive complex 2 (PRC2) methylates lysine 27 in histone H3, a modification associated with epigenetic gene silencing. This complex plays a fundamental role in regulating cellular differentiation and development, and PRC2 overexpression and mutations have been implicated in numerous cancers.
Lindsay E, Moritz, Raymond C, Trievel
openaire   +2 more sources

Repression of IS200 transposase synthesis by RNA secondary structures [PDF]

Nucleic Acids Research, 1999
The IS 200 transposase, a 16 kDa polypeptide encoded by the single open reading frame (ORF) of the insertion element, has been identified using an expression system based on T7 RNA polymerase. In wild-type IS 200, two sets of internal inverted repeats that generate RNA secondary structures provide two independent mechanisms for repression of ...
Beuzón López, Carmen del Rosario, Marqués, Silvia, Casadesús Pursals, Josep   +2 more
openaire   +3 more sources

Structural mechanism of HP1α-dependent transcriptional repression and chromatin compaction

Structure, 2023
Abstract Heterochromatin protein 1 (HP1) plays a central role in establishing and maintaining constitutive heterochromatin. However, the mechanisms underlying HP1-nucleosome interactions and their contributions to heterochromatin functions remain elusive.
Vladyslava Sokolova, Jacob Miratsky, Vladimir Svetlov, Michael Brenowitz, John Vant, Tyler S. Lewis, Kelly Dryden, Gahyun Lee, Shayan Sarkar, Evgeny Nudler, Abhishek Singharoy, Dongyan Tan   +11 more
openaire   +3 more sources

Repressive security and civil society in France

, 2021
Published: 07 September 2021Counter-terrorism in France is understood, for the purpose of this chapter, as being structured around the three key areas: race, religion and criminality. Upon these three themes, the structures of security within a post 9/11
MCNEIL-WILLSON, Richard, MATHEWS, Priya Sara   +1 more
core   +1 more source

Structure theorems and the dynamics of nitrogen catabolite repression in yeast [PDF]

Proceedings of the National Academy of Sciences, 2005
By using current biological understanding, a conceptually simple, but mathematically complex, model is proposed for the dynamics of the gene circuit responsible for regulating nitrogen catabolite repression (NCR) in yeast. A variety of mathematical “structure” theorems are described that allow one to determine the asymptotic dynamics of complicated ...
Erik M, Boczko, Terrance G, Cooper, Tomas, Gedeon, Konstantin, Mischaikow, Deborah G, Murdock, Siddharth, Pratap, K Sam, Wells   +6 more
openaire   +2 more sources

Repressive and non-repressive chromatin at native telomeres in Saccharomyces cerevisiae [PDF]

, 2009
Background In Saccharomyces cerevisiae genes that are located close to a telomere can become transcriptionally repressed by an epigenetic process known as telomere position effect.
Esther R Loney, Pryde, Fiona E., Louis Edward J, Pryde, FE, F. E. Pryde (7675940), Mellor, J., P. W. Inglis (7675937), Nicholas A Kent, J. Mellor (27566), Pryde Fiona E, Mellor Jane, Sharp Sarah, Kent Nicholas A, Loney, E. R., Sharp, Sarah, Sharp, S., Edward John Louis (7604981), Sharp, S, Kent, NA, S. Sharp (7639394), Inglis, Peter W., Louis, Edward J., Inglis, P. W., Inglis, PW, N. A. Kent (7675943), Peter W Inglis, Loney, Esther R., Kent, Nicholas A., Jane Mellor, Mellor, J, Edward J Louis, Pryde, F. E., Louis, E. J., Loney Esther R, Inglis Peter W, Loney, ER, Louis, EJ, E. R. Loney (7675934), Mellor, Jane, Fiona E Pryde, Sarah Sharp   +40 more
core   +1 more source

Structural Basis for Retinoic X Receptor Repression on the Tetramer [PDF]

Journal of Biological Chemistry, 2011
Retinoic X receptor (RXR) is a master nuclear receptor in the processes of cell development and homeostasis. Unliganded RXR exists in an autorepressed tetramer, and agonists can induce RXR dimerization and coactivator recruitment for activation. However, the molecular mechanisms involving the corepressor recruitment and antagonist-mediated repression ...
Haitao, Zhang, Lili, Chen, Jing, Chen, Hualiang, Jiang, Xu, Shen   +4 more
openaire   +2 more sources