RGS12TS-S Localizes at Nuclear Matrix-Associated Subnuclear Structures and Represses Transcription: Structural Requirements for Subnuclear Targeting and Transcriptional Repression [PDF]
RGS12TS-S, an 1,157-amino-acid RGS protein (regulator of G protein signaling), is a nuclear protein that exhibits a unique pattern of subnuclear organization into nuclear foci or dots when expressed endogenously or ectopically. We now report that RGS12TS-S is a nuclear matrix protein and identify structural determinants that target this protein to the ...
Tapan K, Chatterjee, Rory A, Fisher
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Structural basis of RNA polymerase III transcription repression by Maf1 [PDF]
ABSTRACT Maf1 is a highly conserved central regulator of transcription by RNA polymerase III (Pol III), and Maf1 activity influences a wide range of phenotypes from metabolic efficiency to lifespan. Here, we present a 3.3 Å cryo-EM structure of yeast Maf1 bound to Pol III, which establishes how Maf1 achieves transcription repression. In
Vorländer, Matthias K. +6 more
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Interleukin-6 repression is associated with a distinctive chromatin structure of the gene [PDF]
Expression of the interleukin-6 (IL-6) gene is usually tightly controlled and may be induced in specific tissues only after treatment with appropriate stimuli. The molecular mechanisms responsible for IL-6 gene repression in specific tissues or cell lines remain poorly defined.
ARMENANTE F. +4 more
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Usage of secret servise files in Germany
The buildings of the State Security Service in Germany were taken over by human rights activists in autumn 1989. During the initial phase of the peaceful revolution, files were handed over to citizens for safekeeping.
Gunter Bormann
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Chromatin structure of transcriptionally competent and repressed genes. [PDF]
We have compared transcriptionally competent and repressed genes with respect to their linker histone content and their ability to fold into higher-order structures. Histones were cross-linked covalently to DNA in chicken erythrocyte and oviduct nuclei by UV irradiation, and the DNA that was immunoprecipitated with anti-H1 and (for erythrocytes) anti ...
R T, Kamakaka, J O, Thomas
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This article examines the relation between emergency legal doctrine and racial sovereignty in the context of Palestine. It theorises Israel’s multifarious emergency modalities in a colonial present paradigm where traditional territorial colonisation ...
John Reynolds, Reynolds, John
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Inner Prison of the NKGB (MGB, KGB) of Lithuanian Soviet Socialist Republic 1944–1959
This study discloses the 1944-1959 period history of the inner prison of NKGB (Narodny Komissariat Gosudarstvennoy bezopasnosti, English translation – The People‘s Commissariat for State Security) of Lithuanian Soviet Socialist Republic, including MGB ...
Darius Indrišionis
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Structure and Function of the Polycomb Repressive Complexes PRC1 and PRC2
Epigenetic regulation contributes to the control of gene expression programs through local chromatin rearrangements [...]
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Armed Soviet and Party Activists and Other Paramilitary Units
In the second half of 1945, the occupiers, convinced that it would be difficult to break the resistance of our people with harsh military force, began to implement the directive of 12 October 1945 issued by the People’s Commissar of the NKVD, Lavrentiy ...
Juozas Starkauskas
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A role for repressive complexes and H3K9 di-methylation in PRDM5-associated brittle cornea syndrome [PDF]
Contains fulltext : 152261.pdf (Publisher’s version ) (Open Access)Type 2 brittle cornea syndrome (BCS2) is an inherited connective tissue disease with a devastating ocular phenotype caused by mutations in the transcription factor PR ...
Elcioglu, Mustafa +32 more
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