Results 61 to 70 of about 30,587 (268)

Structural basis of JAZ repression of MYC transcription factors in jasmonate signalling [PDF]

Nature, 2015
The plant hormone jasmonate plays crucial roles in regulating plant responses to herbivorous insects and microbial pathogens and is an important regulator of plant growth and development. Key mediators of jasmonate signalling include MYC transcription factors, which are repressed by jasmonate ZIM-domain (JAZ) transcriptional repressors in the resting ...
Zhang, Feng, Yao, Jian, Ke, Jiyuan, Zhang, Li, Lam, Vinh Q, Xin, Xiu-Fang, Zhou, X Edward, Chen, Jian, Brunzelle, Joseph, Griffin, Patrick R, Zhou, Mingguo, Xu, H Eric, Melcher, Karsten, He, Sheng Yang   +13 more
openaire   +2 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Repression and activation by multiprotein complexes that alter chromatin structure. [PDF]

Genes & Development, 1996
Recent studies have provided strong evidence that macromolecular complexes are used in the cell to remodel chromatin structure during activation and to create an inaccessible structure during repression, Although there is not yet any rigorous demonstration that modification of chromatin structure plays a direct, causal role in either activation or ...
R E, Kingston, C A, Bunker, A N, Imbalzano   +2 more
openaire   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

About one more Organ of the Stalinist Period – Troikas and Petiorkas

Genocidas ir Rezistencija, 2002
Informal formations of party and chekist organs – troykas, chetvyortkas, petyorkas – were formed on the instructions of the Lithuanian Bureau of the Central Committee of the Communist Party of Lithuania (LKP(b)); they began their more active operations ...
Juozas Starkauskas
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

The NKGB–NKVD Actions Against Polish Underground in Lithuania in 1944–1945

Genocidas ir Rezistencija, 1999
The Soviet Union has never considered the Armija Krajowa (AK) its ally and made every effort to annihilate the armed underground movement of Poles in Lithuania.
Arūnas Bubnys
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

USSR NKGB–MGB structure

Genocidas ir Rezistencija, 1997
This article presents the evolution of the Soviet repressive structures: how many divisions there were and how they changed during the Stalinist period.
Aleksandras Kokurinas
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source