Results 281 to 290 of about 2,089,944 (391)

Correlation Between Irisin and Cognitive Functions in Alzheimer Dementia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The myokine irisin, a recent positive mediator of exercise in the brain, shows neuroprotective functions against Alzheimer's disease (AD). The association between irisin and cognition has never been explored in a biologically defined cohort of patients.
Patrizia Pignataro, Manuela Dicarlo, Chiara Zecca, Daniele Urso, Maria Teresa Dell'Abate, Davide Vilella, Francesco Borlizzi, Roberta Zerlotin, Angela Oranger, Graziana Colaianni, Silvia Colucci, Maria Grano, Giancarlo Logroscino   +12 more
wiley   +1 more source

Developing artificial intelligence tools for institutional review board pre-review: A pilot study on ChatGPT's accuracy and reproducibility. [PDF]

PLOS Digit Health
Fukataki Y, Hayashi W, Nishimoto N, Ito YM.   +3 more
europepmc   +1 more source

ON THE BIOLOGICAL ASSAY OF TOXICITY OF PERTUSSIS VACCINE USING MICE* I. SELECTION OF RESPONSE METAMETER AND REPRODUCIBILITY OF RELATIVE TOXICITY

, 1962
MASAMI KUROKAWA, Kazuo Kuratsuka, Kiichi Horie, SETSUJI ISHIDA, Yujiro FUJISAKI, Junkai Irisawa, Y. Shimazaki, ISAMU FUNASAKA, CHIEKO OSUGI   +8 more
openalex   +2 more sources

The Comparative Effectiveness and Tolerability of Sphingosine‐1‐Phosphate Receptor Modulators in Patients With Multiple Sclerosis: A Network Meta‐Analysis of Randomized Controlled Trials

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Sphingosine‐1‐phosphate receptor modulators (S1PRM) are used to treat relapsing multiple sclerosis (MS). Each drug has a different S1PR‐subtype selectivity. They target the G‐protein coupled S1P receptors and exert significant immunomodulatory effects, such as preventing the formation of new CNS lesions and the reactivation of pre ...
Faizan Shahzad, Taimoon Rasheed, Momina Riaz Siddiqui, Hamza Hamid, Marwah Bintay Khalid, Haroon Shabbir, Besher Shami, Abdullah, Syed Ijlal Ahmed   +8 more
wiley   +1 more source

Reproducibility and quality assurance in MRI. [PDF]

MAGMA
Stöcker T, Keenan KE, Knoll F, Priovoulos N, Uecker M, Zaitsev M.   +5 more
europepmc   +1 more source

An empirical analysis of journal policy effectiveness for computational reproducibility

Proceedings of the National Academy of Sciences of the United States of America, 2018
V. Stodden, Jennifer Seiler, Zhaokun Ma
semanticscholar   +1 more source

Identification of Dementia With Lewy Bodies by Skin Biopsy in Recent‐Onset Cognitive Impairment

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Immunofluorescence for phosphorylated alpha‐synuclein in skin biopsy samples is an emerging biomarker in synucleinopathies comprising Dementia with Lewy bodies. In this pilot study, 19 patients with recent‐onset (≤ 18 months) cognitive impairment underwent skin biopsy at baseline, with follow‐up clinical re‐evaluation.
Alessandro Furia, Alex Incensi, Cecilia Delprete, Giovanni Rizzo, Salvatore Bonvegna, Marco Piatti, Enrica Olivola, Francesco Ventruto, Veria Vacchiano, Enrico Fileccia, Roberto Cilia, Nicola Modugno, Rocco Liguori, Vincenzo Donadio   +13 more
wiley   +1 more source

A comparative analysis of myocardial strain and strain rate in cardiac computed tomography and magnetic resonance feature tracking. [PDF]

Radiol Med
Del-Canto I, López-Lereu MP, Monmeneu JV, Maceira A, Moratal D.   +4 more
europepmc   +1 more source

Opinion: Is science really facing a reproducibility crisis, and do we need it to?

Proceedings of the National Academy of Sciences of the United States of America, 2018
D. Fanelli
semanticscholar   +1 more source

Cognitive Resilience in Apolipoprotein ε4 Carrier Women Predicted by Neuron‐Derived Extracellular Vesicles

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The Apolipoprotein (APOE) ε4 allele is the strongest genetic risk factor for late‐onset Alzheimer's disease (AD); however, many ε4 carriers remain cognitively intact into old age. Leveraging plasma neuron‐derived extracellular vesicles (NDEVs), we sought to identify biomarkers of cognitive resilience and their interplay with APOE ...
Apostolos Manolopoulos, Maja Mustapic, Carlos Nogueras‐Ortiz, Francheska Delgado‐Peraza, Krishna A. Pucha, Pamela J. Yao, Joseph Blommer, Michael P. Vreones, William York, De' Larrian Knight, Stephen R. Rapp, Aladdin H. Shadyab, JoAnn E. Manson, Ramon Casanova, Robert B. Wallace, Luigi Ferrucci, Susan M. Resnick, Dimitrios Kapogiannis   +17 more
wiley   +1 more source