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Experiments from unfinished Registered Reports in the Reproducibility Project: Cancer Biology
eLife, 2021 As part of the Reproducibility Project: Cancer Biology , we published Registered Reports that described how we intended to replicate selected experiments from 29 high-impact preclinical cancer biology papers published between 2010 and 2012.
Timothy M Errington +27 more
openaire +4 more sources
Investigating the replicability of preclinical cancer biology
eLife, 2021 Replicability is an important feature of scientific research, but aspects of contemporary research culture, such as an emphasis on novelty, can make replicability seem less important than it should be.
Timothy M. Errington +6 more
semanticscholar +1 more source
Challenges for assessing replicability in preclinical cancer biology
eLife, 2021 We conducted the Reproducibility Project: Cancer Biology to investigate the replicability of preclinical research in cancer biology. The initial aim of the project was to repeat 193 experiments from 53 high-impact papers, using an approach in which the ...
Timothy M. Errington +4 more
semanticscholar +1 more source
Is preclinical research in cancer biology reproducible enough?
eLife, 2021 The Reproducibility Project: Cancer Biology (RPCB) was established to provide evidence about reproducibility in basic and preclinical cancer research, and to identify the factors that influence reproducibility more generally.
P. Kane, J. Kimmelman
semanticscholar +1 more source
Science AMA Series: We’re the Reproducibility Project: Cancer Biology team. AUA! [PDF]
, 2017 This month, as part of the Reproducibility Project: Cancer Biology (RP:CB), we published the results of our first five Replication Studies in the journal eLife. We plan to complete 20+ more replication studies, along with a final meta analysis of all studies conducted for RP:CB. Ultimately, the goal is to investigate the overall rate of reproducibility
null Cancer_Reproduction, r/Science AMAs
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Replication of"null results"-- Absence of evidence or evidence of absence? [PDF]
, 2023 In several large-scale replication projects, statistically non-significant results in both the original and the replication study have been interpreted as a"replication success".
Samuel Pawel +3 more
semanticscholar +1 more source
An open investigation of the reproducibility of cancer biology research
eLife, 2014 It is widely believed that research that builds upon previously published findings has reproduced the original work. However, it is rare for researchers to perform or publish direct replications of existing results.
Timothy M. Errington +5 more
semanticscholar +1 more source
eLife, 2020 As part of the Reproducibility Project: Cancer Biology we published a Registered Report (Khan et al., 2015), that described how we intended to replicate selected experiments from the paper "A coding-independent function of gene and pseudogene mRNAs ...
J. Kerwin +6 more
semanticscholar +1 more source