Results 11 to 20 of about 7,412 (168)
eLife, 2021 As the final outputs of the Reproducibility Project: Cancer Biology are published, it is clear that preclinical research in cancer biology is not as reproducible as it should be.
P. Rodgers, Andrew M. Collings
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British Journal of Pharmacology, 2018 Reproducibility is a current concern for everyone involved in the conduct and publication of biomedical research. Recent attempts testing reproducibility, particularly the reproducibility project in cancer biology published in elife (https ...
S. Alexander +16 more
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eLife, 2017 In 2015, as part of the Reproducibility Project: Cancer Biology, we published a Registered Report (Kandela et al., 2015) that described how we intended to replicate selected experiments from the paper “Coadministration of a tumor-penetrating peptide ...
Christine Mantis +2 more
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Replication Study: Systematic identification of genomic markers of drug sensitivity in cancer cells
eLife, 2018 In 2016, as part of the Reproducibility Project: Cancer Biology, we published a Registered Report (Vanden Heuvel et al., 2016), that described how we intended to replicate selected experiments from the paper ‘Systematic identification of genomic markers ...
J. P. Vanden Heuvel +7 more
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eLife, 2019 As part of the Reproducibility Project: Cancer Biology, we published a Registered Report (Li et al., 2015), that described how we intended to replicate selected experiments from the paper ‘The microRNA miR-34a inhibits prostate cancer stem cells and ...
Xue-Fei Yan +9 more
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Can cancer researchers accurately judge whether preclinical reports will reproduce?
PLoS Biology, 2017 There is vigorous debate about the reproducibility of research findings in cancer biology. Whether scientists can accurately assess which experiments will reproduce original findings is important to determining the pace at which science self-corrects. We
Daniel M. Benjamin +2 more
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eLife, 2015 The Reproducibility Project: Cancer Biology seeks to address growing concerns about reproducibility in scientific research by conducting replications of selected experiments from a number of high-profile papers in the field of cancer biology. The papers,
Jia Li +2 more
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Registered report: A chromatin-mediated reversible drug-tolerant state in cancer cell subpopulations
eLife, 2016 The Reproducibility Project: Cancer Biology seeks to address growing concerns about reproducibility in scientific research by conducting replications of selected experiments from a substantial number of high-profile papers in the field of cancer biology.
Babette Haven +5 more
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Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
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Registered report: Diverse somatic mutation patterns and pathway alterations in human cancers
eLife, 2016 The Reproducibility Project: Cancer Biology seeks to address growing concerns about reproducibility in scientific research by conducting replications of selected experiments from a number of high-profile papers in the field of cancer biology. The papers,
Vidhu Sharma +3 more
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