Results 101 to 110 of about 1,117,074 (345)

Updates to data versions and analytic methods influence the reproducibility of results from epigenome-wide association studies. [PDF]

open access: yesEpigenetics, 2022
Lussier AA   +8 more
europepmc   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Validity of content and face validity of the instrument "Perception of behaviors of harmonized care" Validez de contenido y validez facial del instrumento "Percepción de comportamientos de cuidado humanizado" Validade de conteúdo e validade facial do instrumento "Percepção de comportamentos de cuidado humanizado"

open access: yesAvances en Enfermería, 2008
A methodological research was carried out whose objective was to determine the face validity and content validity of the instrument "Perception of behaviors of humanized nursing care" of Rivera and Triana, with twelve patients and/or their permanent care
VARGAS ROSERO ELIZABETH   +1 more
doaj  

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

open access: yesMolecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard   +12 more
wiley   +1 more source

Epitaxial silicon growth for solar cells [PDF]

open access: yes
Growth and fabrication procedures for the baseline solar cells are described along with measured cell parameters, and the results. Reproducibility of these results was established and the direction to be taken for higher efficiency is ...
Daiello, R. V.   +2 more
core   +1 more source

Measuring reproducibility of high-throughput experiments

open access: yes, 2011
Reproducibility is essential to reliable scientific discovery in high-throughput experiments. In this work we propose a unified approach to measure the reproducibility of findings identified from replicate experiments and identify putative discoveries ...
Bickel, Peter J.   +3 more
core   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

Reading and interpretation of chest X-ray in adults with community-acquired pneumonia

open access: yesBrazilian Journal of Infectious Diseases
INTRODUCTION: Traditional reading of chest X-rays usually has a low prognostic value and poor agreement. OBJECTIVE: This study aimed to determine the interobserver and intraobserver agreement using two reading formats in patients with community-acquired ...
Diana Carolina Moncada   +5 more
doaj   +1 more source

Utilizing stability criteria in choosing feature selection methods yields reproducible results in microbiome data [PDF]

open access: green, 2020
Lingjing Jiang   +9 more
openalex   +1 more source

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