Results 101 to 110 of about 723,854 (310)

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Updates to data versions and analytic methods influence the reproducibility of results from epigenome-wide association studies. [PDF]

open access: yesEpigenetics, 2022
Lussier AA   +8 more
europepmc   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Repeatability and reproducibility of measurements of the suburethral tape location obtained in pelvic floor ultrasound performed with a transvaginal probe [PDF]

open access: yes, 2017
Introduction: Implants used to treat patients with urogynecological conditions are well visible in US examination. The position of the suburethral tape (sling) is determined in relation to the urethra or the pubic symphysis. Aim of the study: The study
Kociszewski, Jacek   +11 more
core   +1 more source

Validez interna y reproducibilidad de la prueba CAGE en Bucaramanga, Colombia.

open access: yesBiomédica: revista del Instituto Nacional de Salud, 2005
Objetivo. Evaluar la validez interna y la reproducibilidad de cutting down, annoyance by criticism, guilty feeling, and eye-openers (CAGE) en Bucaramanga, Colombia, de junio de 2002 a noviembre de 2003. Método.
Oscar F. Herrán, María F. Ardila
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Research method in AI - Reproducibility of results [PDF]

open access: yes, 2017
Reproducibility of published computational research has seen increased interest the last twenty years. Regardless of academic field and the impact-factor of journals, studies of reproducibility of computational research have found low rates of ...
Kjensmo, Sigbjørn
core  

Two universality results for polynomial reproducing kernels

open access: yesJournal of Approximation Theory, 2017
We prove two new universality results for polynomial reproducing kernels of compactly supported measures. The first applies to measures on the unit circle with a jump and a singularity in the weight at $1$ and the second applies to area-type measures on a certain disconnected polynomial lemniscate.
openaire   +3 more sources

Home - About - Disclaimer - Privacy