Results 111 to 120 of about 1,463,180 (385)

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

FEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz, Milagros Siebeck Caturelli, Lina S. Lehmann, Florian Kurth, Alexander G. Maier, Kai Matuschewski   +5 more
wiley   +1 more source

Results of von Neumann analyses for reproducing kernel semi-discretizations [PDF]

, 2000
M Christon, Thomas E. Voth
openalex   +3 more sources

Reading and interpretation of chest X-ray in adults with community-acquired pneumonia

Brazilian Journal of Infectious Diseases
INTRODUCTION: Traditional reading of chest X-rays usually has a low prognostic value and poor agreement. OBJECTIVE: This study aimed to determine the interobserver and intraobserver agreement using two reading formats in patients with community-acquired ...
Diana Carolina Moncada, Zulma Vanessa Rueda, Antonio Macías, Tatiana Suárez, Héctor Ortega, Lázaro Agustín Vélez   +5 more
doaj   +1 more source

The role of fibroblast growth factors in cell and cancer metabolism

FEBS Letters, EarlyView.
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley   +1 more source

BEAT: An Open-Source Web-Based Open-Science Platform [PDF]

, 2017
With the increased interest in computational sciences, machine learning (ML), pattern recognition (PR) and big data, governmental agencies, academia and manufacturers are overwhelmed by the constant influx of new algorithms and techniques promising ...
Anjos, André, El-Shafey, Laurent, Marcel, Sébastien   +2 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Data Sharing and Reproducibility of Results-Does It Matter for HIV Nursing? [PDF]

J Assoc Nurses AIDS Care, 2021
Relf MV, Overstreet K.
europepmc   +1 more source

Enabling the Verification of Computational Results: An Empirical Evaluation of Computational Reproducibility

Proceedings of the First International Workshop on Practical Reproducible Evaluation of Computer Systems, 2018
The ability to independently regenerate published computational claims is widely recognized as a key component of scientific reproducibility. In this article we take a narrow interpretation of this goal, and attempt to regenerate published claims from ...
V. Stodden, Matthew Scott Krafczyk, A. Bhaskar   +2 more
semanticscholar   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Intra and Interobserver Agreement Regarding the Walch Classification System for Shoulder Joint Arthritis [PDF]

Revista Brasileira de Ortopedia
Objective To evaluate the inter- and intraobserver agreement regarding the Walch classification system for shoulder arthritis. Methods Computed tomography scans of the shoulder joint of adult patients were selected between 2012 and 2016, and they were ...
Lauro José Rocchetti Pajolli, Marcelo Casciato Carlini, Isabella Ferrari, Fábio Teruo Matsunaga, Nicola Archetti Netto, Marcel Jun Sugawara Tamaoki   +5 more
doaj   +4 more sources