Results 141 to 150 of about 1,463,180 (385)
A resistance strain gage with repeatable and cancellable apparent strain for use to 800 C [PDF]
A temperature compensated static strain gage, which is fabricated from palladium-13w/o chromium (Pd13Cr) alloy and a platinum (Pt) compensator, is being developed and was tested over a temperature range to 800 C at NASA-Lewis. The PdCr compensated strain
Lei, Jih-Fen
core +1 more source
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop +10 more
wiley +1 more source
Background and Objectives: Falling is one of the important concerns of older adults and is associated with a series of constraints, such as decline in social activities, general physical weakness, physical activities avoidance, and decrease in quality of
Daryoush Khajavi +1 more
doaj
Leveraging Semantics to Improve Reproducibility in Scientific Workflows [PDF]
Reproducibility of published results is a cornerstone in scientific publishing and progress. Therefore, the scientific community has been encouraging authors and editors to publish their contributions in a verifiable and understandable way.
Corcho, Oscar +5 more
core
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source
Objective: A) To evaluate the reliability of a new technique for the measurement of both intermetatarsal and hallux valgus angles. B) To evaluate whether this technique can be performed with the aid of a smartphone application.
Luis Felipe Cortês Padilha +5 more
doaj
Erratum: Effective-mass reproducibility of the nearest-neighbor
Timothy B. Boykin +3 more
openalex +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias +12 more
wiley +1 more source
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim +11 more
wiley +1 more source

