Results 241 to 250 of about 4,106,574 (383)

Iron‐dependent lysosomal LDL oxidation induces the expression of scavenger receptor A in human THP‐1 monocytes

FEBS Open Bio, EarlyView.
In human monocytic cells THP‐1, a limited uptake of native—not oxidized—LDL/VLDL induced expression of scavenger receptor A and cellular adhesion. Induction was inhibited by lysosomotropic (WR‐1065) and lipophilic (BHT) antioxidants and by siRNAs against ferritinophagy.
Martina Čierna, Richard Buchal, Martin Leníček, Amit Shachak, Jan Pláteník   +4 more
wiley   +1 more source

LISC 2013 - Results: Discussion Groups on Semantic Web and Reproducibility

, 2013
Paul Groth, Peter Ansell, Kjetil Kjernsmo, Jacco van Ossenbruggen, Guillermo Palma, Carol Goble, María-Esther Vidal, Cameron McLean, Richard Hosking, Steve Cassidy, Jun Zhao, Prashant Gupta, Niels Ockeloen, Graham Klyne   +13 more
openalex   +2 more sources

Active Maintenance: A Proposal for the Long-Term Computational Reproducibility of Scientific Results

, 2021
Limor Peer, Lilla Orr, Alexander Coppock
openalex   +2 more sources

Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies

FEBS Open Bio, EarlyView.
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa, Ilva Liekniņa, Svetlana Koteloviča, Ramona Petrovska, Gediminas Žvinys, Agne Petrosiute, Asta Zubrienė, Matīss Toms Laugalis, Vendija Skeltona, Juris Jansons, Madara Kreishmane, Edita Čapkauskaitė, Daumantas Matulis, Kaspars Tārs   +13 more
wiley   +1 more source

Knockout of the mitoribosome rescue factors Ict1 or Mtrfr is viable in zebrafish but not mice: compensatory mechanisms underlying each factor's loss

FEBS Open Bio, EarlyView.
Mitochondria contain two mitoribosome rescue factors, ICT1 and MTRFR (C12orf65). ICT1 also functions as a mitoribosomal protein in mice and humans, and its loss is lethal. Although Mtrfr knockout mice could not be generated, knockout zebrafish lines for ict1 and mtrfr were established.
Nobukazu Nameki, Chika Tomisawa, Soichiro Hoshino, Hidehiko Shimizu, Masashi Abe, Sho Arai, Kanako Kuwasako, Naoki Asakawa, Yusuke Inoue, Takuro Horii, Izuho Hatada, Masakatsu Watanabe   +11 more
wiley   +1 more source

EP-1212: Are the encouraging SABR results for NSCLC reproducible outside of pioneering academic institutions?

, 2016
C. Peedell, E. Aynsley, David Shakespeare, J. Green, P Summers, John M. Reynolds, Kristin E. Burke, H. Bayles, Christopher D. Huntley, Neil D. Richmond   +9 more
openalex   +1 more source

The DIARieS ecosystem – A software ecosystem to simplify discovery, implementation, analysis, reproducibility, and sharing of scientific results and environments in Heliophysics

, 2022
Rebecca Ringuette, Alec Engell, Oliver Gerland, Ryan McGranaghan, B. J. Thompson   +4 more
openalex   +1 more source

Short peptide perturbs spermatogenesis via immune microenvironment dysregulation and mitochondrial imbalance

FEBS Open Bio, EarlyView.
In the blood–testis barrier, occludin is crucial for tight junctions. This study demonstrates that occludin‐targeting short peptides disrupt junction integrity, inducing immune cell infiltration, tumor necrosis factor‐α/interleukin‐6 secretion and mitochondrial dysfunction, ultimately triggering apoptosis.
Heng Wang, Xiaofang Tan, Deyu Chen
wiley   +1 more source

Repeatability and reproducibility of Keratograph 5M corneal topography. [PDF]

PeerJ
Ortiz-Toquero S, Sanchez I, Martin R.
europepmc   +1 more source

Modified arthroscopic latarjet procedure with paired-endobutton: A safe, rigid, and reproducible technique with early results

, 2016
Wei Lü, Daping Wang, Weiming Zhu
openalex   +1 more source