Results 41 to 50 of about 115,296 (125)
eLife, 2015 The Reproducibility Project: Cancer Biology seeks to address growing concerns about reproducibility in scientific research by conducting replications of 50 papers in the field of cancer biology published between 2010 and 2012.
I. Kandela +3 more
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eLife, 2015 The Reproducibility Project: Cancer Biology seeks to address growing concerns about reproducibility in scientific research by conducting replications of selected experiments from a number of high-profile papers in the field of cancer biology. The papers,
Israr Khan +4 more
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Reference environments: A universal tool for reproducibility in computational biology [PDF]
arXiv, 2018 The drive for reproducibility in the computational sciences has provoked discussion and effort across a broad range of perspectives: technological, legislative/policy, education, and publishing. Discussion on these topics is not new, but the need to adopt standards for reproducibility of claims made based on computational results is now clear to ...
arxiv
No crisis should go to waste [PDF]
arXiv, 2016 The crisis in the reproducibility of experiments invites a re-evaluation of methods of inquiry and validation procedures. The text challenges current assumptions of knowledge acquisition and introduces G-complexity for defining decidable vs. non-decidable knowledge domains.
arxiv
eLife, 2017 The first results from the Reproducibility Project: Cancer Biology suggest that there is scope for improving reproducibility in pre-clinical cancer research.
Brian A. Nosek, Timothy M. Errington
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Replication of null results: Absence of evidence or evidence of absence?
eLifeIn several large-scale replication projects, statistically non-significant results in both the original and the replication study have been interpreted as a ‘replication success.’ Here, we discuss the logical problems with this approach: Non-significance
Samuel Pawel +3 more
semanticscholar +1 more source
Perturbation Biology: inferring signaling networks in cellular systems [PDF]
, 2013 We present a new experimental-computational technology of inferring network models that predict the response of cells to perturbations and that may be useful in the design of combinatorial therapy against cancer. The experiments are systematic series of perturbations of cancer cell lines by targeted drugs, singly or in combination.
arxiv +1 more source
eLife, 2017 In 2015, as part of the Reproducibility Project: Cancer Biology, we published a Registered Report (Chroscinski et al., 2015) that described how we intended to replicate selected experiments from the paper “The CD47-signal regulatory protein alpha (SIRPa)
S. Horrigan +1 more
semanticscholar +1 more source
Tangled Nature: a model of evolutionary ecology [PDF]
arXiv, 2001 We discuss a simple model of co-evolution. In order to emphasise the effect of interaction between individuals the entire population is subjected to the same physical environment. Species are emergent structures and extinction, origination and diversity are entirely a consequence of co-evolutionary interaction between individuals.
arxiv
Replication Study: Fusobacterium nucleatum infection is prevalent in human colorectal carcinoma
eLife, 2018 As part of the Reproducibility Project: Cancer Biology, we published a Registered Report (Repass et al., 2016), that described how we intended to replicate an experiment from the paper ‘Fusobacterium nucleatum infection is prevalent in human colorectal ...
J. Repass +5 more
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