Results 91 to 100 of about 871,682 (287)

Sciunits: Reusable Research Objects

open access: yes, 2017
Science is conducted collaboratively, often requiring knowledge sharing about computational experiments. When experiments include only datasets, they can be shared using Uniform Resource Identifiers (URIs) or Digital Object Identifiers (DOIs).
Fils, Gabriel   +3 more
core   +1 more source

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi   +5 more
wiley   +1 more source

Caching and Distributing Statistical Analyses in R

open access: yesJournal of Statistical Software, 2008
We present the cacher package for R, which provides tools for caching statistical analyses and for distributing these analyses to others in an efficient manner.
Roger D. Peng
doaj  

Accessible Reproducible Research [PDF]

open access: yesScience, 2010
As use of computation in research grows, new tools are needed to expand recording, reporting, and reproduction of methods and data.
openaire   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

RR by R in Official Statistics [PDF]

open access: yesRevista Română de Statistică, 2016
Nowadays there is a growing alarm about scientific research results that cannot be reproduced. The reasons comprise increased levels of control, complexity of experiments and statistics, and also time pressures on researchers.
Ciprian ALEXANDRU, Nicoleta CARAGEA
doaj  

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

The Dmipy Toolbox: Diffusion MRI Multi-Compartment Modeling and Microstructure Recovery Made Easy

open access: yesFrontiers in Neuroinformatics, 2019
Non-invasive estimation of brain microstructure features using diffusion MRI (dMRI)—known as Microstructure Imaging—has become an increasingly diverse and complicated field over the last decades.
Rutger H. J. Fick   +3 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Improving the reproducibility in geoscientific papers: lessons learned from a Hackathon in climate science

open access: yesEnvironmental Data Science
In this paper, we explore the crucial role and challenges of computational reproducibility in geosciences, drawing insights from the Climate Informatics Reproducibility Challenge (CICR) in 2023.
Alejandro Coca-Castro   +5 more
doaj   +1 more source

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