Results 121 to 130 of about 614,762 (328)

Open Science and Research Reproducibility

ecancermedicalscience, 2016
Many scientists, journals and funders are concerned about the low reproducibility of many scientific findings. One approach that may serve to improve the reliability and robustness of research is open science. Here I argue that the process of pre-registering study protocols, sharing study materials and data, and posting preprints of manuscripts may ...
openaire   +5 more sources

ReproServer: Making Reproducibility Easier and Less Intensive [PDF]

arXiv, 2018
Reproducibility in the computational sciences has been stymied because of the complex and rapidly changing computational environments in which modern research takes place. While many will espouse reproducibility as a value, the challenge of making it happen (both for themselves and testing the reproducibility of others' work) often outweigh the ...
arxiv  

Subpar reporting of pre‐analytical variables in RNA‐focused blood plasma studies

Molecular Oncology, EarlyView.
Pre‐analytical variables strongly influence the analysis of extracellular RNA (cell‐free RNA; exRNA) derived from blood plasma. Their reporting is essential to allow interpretation and replication of results. By evaluating 200 exRNA studies, we pinpoint a lack of reporting pre‐analytical variables associated with blood collection, plasma preparation ...
Céleste Van Der Schueren, Philippe Decruyenaere, Francisco Avila Cobos, Johanna Bult, Jill Deleu, Laudonia Lidia Dipalo, Hetty Hilde Helsmoortel, Eva Hulstaert, Annelien Morlion, Elena Ramos Varas, Kathleen Schoofs, Wim Trypsteen, Eveline Vanden Eynde, Hanne Van Droogenbroeck, Kimberly Verniers, Jo Vandesompele, Anneleen Decock   +16 more
wiley   +1 more source

Reprowd: Crowdsourced Data Processing Made Reproducible [PDF]

arXiv, 2016
Crowdsourcing is a multidisciplinary research area including disciplines like artificial intelligence, human-computer interaction, database, and social science. To facilitate cooperation across disciplines, reproducibility is a crucial factor, but unfortunately, it has not gotten enough attention in the HCOMP community.
arxiv  

Identification of functional and diverse circulating cancer‐associated fibroblasts in metastatic castration‐naïve prostate cancer patients

Molecular Oncology, EarlyView.
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink, Leon W. M. M. Terstappen, Eshwari Dathathri, Khrystany Isebia, Jaco Kraan, John Martens, Ruchi Bansal   +6 more
wiley   +1 more source

Distributed Reproducible Research Using Cached Computations [PDF]

, 2008
Roger D. Peng, Sandrah P. Eckel
openalex   +1 more source

Towards reproducible machine learning-based process monitoring and quality prediction research for additive manufacturing [PDF]

arXiv
Machine learning (ML)-based cyber-physical systems (CPSs) have been extensively developed to improve the print quality of additive manufacturing (AM). However, the reproducibility of these systems, as presented in published research, has not been thoroughly investigated due to a lack of formal evaluation methods.
arxiv  

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

Molecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi, Jérome Vialaret, Christophe Hirtz, Catherine Alix‐Panabières   +3 more
wiley   +1 more source

The NCI Imaging Data Commons as a platform for reproducible research in computational pathology. [PDF]

Comput Methods Programs Biomed, 2023
Schacherer DP, Herrmann MD, Clunie DA, Höfener H, Clifford W, Longabaugh WJR, Pieper S, Kikinis R, Fedorov A, Homeyer A.   +9 more
europepmc   +1 more source

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

Molecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker, Samantha Hasenleithner, Rupert Bartsch, Simon P. Gampenrieder, Daniel Egle, Christian F. Singer, Gabriel Rinnerthaler, Michael Hubalek, Katja Schmitz, Zsuzsanna Bago‐Horvath, Andreas Petzer, Sonja Heibl, Ellen Heitzer, Marija Balic, Michael Gnant   +14 more
wiley   +1 more source