Results 181 to 190 of about 614,762 (328)

animation : An R Package for Creating Animations and Demonstrating Statistical Methods

Journal of Statistical Software, 2013
Animated graphs that demonstrate statistical ideas and methods can both attract interest and assist understanding. In this paper we first discuss how animations can be related to some statistical topics such as iterative algorithms, random simulations ...
Yihui Xie
doaj  

Respiratory complex I‐mediated NAD+ regeneration regulates cancer cell proliferation through the transcriptional and translational control of p21Cip1 expression by SIRT3 and SIRT7

Molecular Oncology, EarlyView.
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi, Kazunori Mori, Hidetsugu Nakagawa, Momoko Uchida, Fumihiro Ishikawa, Motoko Shibanuma   +5 more
wiley   +1 more source

Reproducibility: Standardize antibodies used in research [PDF]

, 2015
Andrew Bradbury, Andreas Plückthun
openalex   +1 more source

Developing and deploying an integrated workshop curriculum teaching computational skills for reproducible research. [PDF]

J Open Source Educ, 2022
Lapp Z, Sovacool KL, Lesniak N, King D, Barnier C, Flickinger M, Krüger J, Armour CR, Lapp MM, Tallant J, Diao R, Oneka M, Tomkovich S, Anderson JM, Lucas SK, Schloss PD.   +15 more
europepmc   +1 more source

Analysis of comprehensive genomic profiling of solid tumors with a novel assay for broad analysis in clinical diagnostics

Molecular Oncology, EarlyView.
In molecular cancer diagnostics, comprehensive genomic profiling (CGP) is going to replace the small NGS panels since it provides all clinically relevant somatic variants as well as genomic biomarkers with clinical value. Here, we compared two CGP assays and demonstrate that the choice for diagnostic implementation will depend on the specific ...
Guy Froyen, Pieter‐Jan Volders, Ellen Geerdens, Severine Berden, Joni Van der Meulen, Aaron De Cock, Stefanie Vermeire, Jacques Van Huysse, Marie de Barsy, Gabriela Beniuga, Wendy W. J. de Leng, Anne M. L. Jansen, Imke Demers, Zeliha Ozgur, Hendrikus Jan Dubbink, Ernst‐Jan M. Speel, Wilfred F. J. van IJcken, Brigitte Maes   +17 more
wiley   +1 more source

Faculty Opinions recommendation of Deriving chemosensitivity from cell lines: Forensic bioinformatics and reproducible research in high-throughput biology.

, 2009
Kevin Karplus
openalex   +1 more source

Better reporting for better research: a checklist for reproducibility [PDF]

, 2015
Amye Kenall, Scott Edmunds, Laurie Goodman, Liz Bal, Louisa Flintoft, Daniel Shanahan, Tim Shipley   +6 more
openalex   +1 more source

Scaling up reproducible research for single-cell transcriptomics using MetaNeighbor. [PDF]

Nat Protoc, 2021
Fischer S, Crow M, Harris BD, Gillis J.
europepmc   +1 more source

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

Molecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane, Jérôme Ambroise, Cédric van Marcke, Mieke Van Bockstal, Martine Berlière, Christine Galant, Hélène Dano, Médina Lougué, Elena Benidovskaya, Guy Jerusalem, Vincent Bours, Claire Josse, Jérôme Thiry, Aurélie Daumerie, Caroline Bouzin, Cyril Corbet, François P. Duhoux   +16 more
wiley   +1 more source

Opening software, like opening research, is necessary for reproducibility

, 2009
Peter Suber
openalex   +1 more source