Results 81 to 90 of about 614,762 (328)

The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum

open access: yesFEBS Letters, EarlyView.
In Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Foteini Karapanagioti   +3 more
wiley   +1 more source

PACER: Platform for Android Malware Classification, Performance Evaluation and Threat Reporting

open access: yesFuture Internet, 2020
Android malware has become the topmost threat for the ubiquitous and useful Android ecosystem. Multiple solutions leveraging big data and machine-learning capabilities to detect Android malware are being constantly developed.
Ajit Kumar   +5 more
doaj   +1 more source

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

Reproducibility and Practical Adoption of GEOBIA with Open-Source Software in Docker Containers

open access: yesRemote Sensing, 2017
Geographic Object-Based Image Analysis (GEOBIA) mostly uses proprietary software,but the interest in Free and Open-Source Software (FOSS) for GEOBIA is growing.
Christian Knoth, Daniel Nüst
doaj   +1 more source

Research Reproducibility as a Survival Analysis

open access: yesProceedings of the AAAI Conference on Artificial Intelligence, 2021
There has been increasing concern within the machine learning community that we are in a reproducibility crisis. As many have begun to work on this problem, all work we are aware of treat the issue of reproducibility as an intrinsic binary property: a paper is or is not reproducible.
openaire   +3 more sources

Social context prevents heat hormetic effects against mutagens during fish development

open access: yesFEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere   +5 more
wiley   +1 more source

The R Language as a Tool for Biometeorological Research

open access: yesAtmosphere, 2020
R is an open-source programming language which gained a central place in the geosciences over the last two decades as the primary tool for research. Now, biometeorological research is driven by the diverse datasets related to the atmosphere and other ...
Ioannis Charalampopoulos
doaj   +1 more source

miRNA‐29 regulates epidermal and mesenchymal functions in skin repair

open access: yesFEBS Letters, EarlyView.
miRNA‐29 inhibits cell‐to‐cell and cell‐to‐matrix adhesion by silencing mRNA targets. Adhesion is controlled by complex interactions between many types of molecules coded by mRNAs. This is crucial for keeping together the layers of the skin and for regenerating the skin after wounding.
Lalitha Thiagarajan   +10 more
wiley   +1 more source

Reproducibility in Research: Systems, Infrastructure, Culture

open access: yesJournal of Open Research Software, 2017
The reproduction and replication of research results has become a major issue for a number of scientific disciplines. In computer science and related computational disciplines such as systems biology, the challenges closely revolve around the ability to ...
Tom Crick   +2 more
doaj   +1 more source

Using GNU Make to Manage the Workflow of Data Analysis Projects

open access: yesJournal of Statistical Software, 2020
Data analysis projects invariably involve a series of steps such as reading, cleaning, summarizing and plotting data, statistical analysis and reporting.
Peter Baker
doaj   +1 more source

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