Results 161 to 170 of about 11,554,034 (251)

From linear models to deep learning: statistical advances in genomic selection for animal breeding. [PDF]

J Anim Sci Biotechnol
Zhang L, Zhang M, Wang X, Chen C, Wang S, Zhao Y, Zhang Y, Wang R, Liu Y.   +8 more
europepmc   +1 more source

Translational Barriers and AI‐Driven Challenges of Microfluidics‐Enabled Wearables and Implantable Systems in Personalized Medicine

Advanced Science, EarlyView.
An integrative review of microfluidics‐enabled wearables and implantable systems reveals a single‐track translation pipeline, bridging functional biomaterials with clinical utility. Dynamic feedback loops driven by artificial intelligence advance diagnostics toward personalized closed‐loop theranostics.
Ke Huang, Ching Yin Fong, Xin Huang, Bee Luan Khoo   +3 more
wiley   +1 more source

The impact of the exponential Kernel's bandwidth parameter on learning algorithms. [PDF]

Sci Rep
Almahdawi MA.
europepmc   +1 more source

NICE: A Two‐Step Non‐Invasive Framework for Embryo cfDNA Read Enrichment and Quality Assessment

Advanced Science, EarlyView.
The non‐invasive NICE framework, built on an ensemble stacking machine learning model, prioritizes embryos by analyzing cell‐free DNA from spent culture medium. By integrating multimodal signals, including genomic and epigenetic profiles, this automated approach standardizes morphological assessment without human bias, paving the way for more precise ...
Xueya Zhou, Shu Ding, Zhenyi Zhang, Qiaoling Shangguan, Jie Qiao, Peijie Zhou, Yidong Chen   +6 more
wiley   +1 more source

Statistical Methods for Detecting Nonlinear Relationships in Gene Expression and Omics Data: A Review. [PDF]

Int J Mol Sci
Huminiecki Ł.
europepmc   +1 more source

A Unified Hierarchical Multiscale Fusion Framework for Drug–Target Affinity Prediction: From Benchmark Performance to Nanomolar Inhibitor Discovery

Advanced Science, EarlyView.
A multimodal fusion framework integrating sequence, atomic, and fragment representations captures drug–target interactions across multiple scales. The model delivers strong predictive performance and enables efficient virtual screening. Applied to hematopoietic progenitor kinase 1 (HPK1), it identifies structurally diverse inhibitors with nanomolar ...
Shuo Liu, Xiang Zhang, Haixia Feng, Yuquan Li, Xiaoqing Gong, Yong Liang, Xiaojun Yao, Huanxiang Liu   +7 more
wiley   +1 more source

Decision-Making Under Model Misspecification: DRO with Robust Bayesian Ambiguity Sets. [PDF]

Entropy (Basel)
Dellaporta C, O'Hara P, Damoulas T.
europepmc   +1 more source

Decoupling Fabrication From Encoding: DNA‐Addressable Template Microparticles for Large, User‐Defined Optical Barcode Libraries

Advanced Science, EarlyView.
A universal hydrogel microparticle template with five DNA‐addressable domains decouples particle fabrication from barcode writing. Contact‐free multilaminar flow lithography produces >106 templates/h, and post‐fabrication domain‐selective hybridization converts one batch into large, user‐defined optical barcode libraries with robust decoding and re ...
Akihiro Eguchi, Yuichiro Iwamoto, Hinata Tokuda, Haruka Narita, Adrian M. Martin, Sadao Ota   +5 more
wiley   +1 more source

Explicit electrothermal LLP VO₂ model reproducing Preisach like hysteresis for memristive and neuromorphic devices. [PDF]

Sci Rep
Sena BASF, de Almeida LAL.
europepmc   +1 more source

Early Spatial and Contextual Coding Deficits in Hippocampal CA1 Precede Performance Decline in an Alzheimer's Disease Model

Advanced Science, EarlyView.
Two‐photon calcium imaging in behaving 5xFAD mice reveals early CA1 coding deficits before behavioral decline. Task‐related place cell activity and splitter cell trajectory coding are impaired, with reduced retrospective dominance and greater prospective weighting.
Yimei Li, Mary Ann Go, Hualong Zhang, Robertas Aleksynas, Juliana Kim, Mingyang Gao, Seigfred Prado, Magdalena Sastre, Simon R. Schultz   +8 more
wiley   +1 more source