Results 131 to 140 of about 4,209,277 (404)

Targeting carbonic anhydrase IX/XII prevents the anti‐ferroptotic effect of stromal lactic acid in prostate carcinoma

Molecular Oncology, EarlyView.
In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella, Giuseppina Comito, Luigi Ippolito, Erica Pranzini, Marta Iozzo, Giulia Gangarossa, Francesca Virgilio, Silvia Bua, Alessio Nocentini, Giada Sandrini, Nicla Lorito, Marina Bacci, Gabriella Nesi, Pietro Spatafora, Sergio Serni, Claudiu T. Supuran, Andrea Morandi, Paola Chiarugi, Elisa Giannoni   +18 more
wiley   +1 more source

Effects of vaginal vs oral progesterone supplementation before embryo transfer on live birth rates and levels: a randomized trial

Reproduction and Fertility
The increase in frozen embryo transfers (FETs) is a consequence of advances in embryo vitrification and the implementation of genetic screening of embryos.
Gorka Barrenetxea, Olaia Prego, Ricardo Celis, Edurne Martínez, María De Las Heras, Oihane Gómez, Olaia Aguirre, Sheila Samojluk, Julen Barrenetxea   +8 more
doaj   +1 more source

HACCP for Reproduction and Farrowing Problems [PDF]

, 2011
Deliverables of the COREPIG project are management tools based on the HACCP principle (Hazard Analysis Critical Control Points). These tools help farmers (in a farm specific way) to solve and prevent problems with endoparasites, reproduction and ...
Dippel, Sabine, Früh, Barbara, Leeb, Christine   +2 more
core  

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

Molecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima, Yuko Takami, Ken Kawabe, Kazuhiro Tanabe, Chihiro Hayashi, Mikio Mikami, Tetsuya Kusumoto   +6 more
wiley   +1 more source

Gut microbiota biodiversity indices as markers of hyperandrogenemia in women of reproductive age

Acta Biomedica Scientifica
Introduction. Previously, it was shown that the “classic” phenotypes of polycystic ovarian syndrome (PCOS) are associated with significant decrease in gut microbiota alpha diversity as compared with healthy women.The aim of the study.
I. A. Igumnov, N. L. Belkova, A. V. Atalyan, E. S. Klimenko, L. F. Sholokhov, L. V. Belenkaia, Ya. M. Samarina, I. N. Danusevich, L. M. Lazareva, Ia. G. Nadeliaeva, L. V. Suturina   +10 more
doaj   +1 more source

Comparative study between agonist and antagonist protocols in PCOS patients undergoing ICSI: a cross-sectional study

Middle East Fertility Society Journal, 2019
Background Polycystic ovary syndrome (PCOS) is one of the most common endocrinopathies affecting 5–10% of women of reproductive age. The syndrome is surrounded by controversies regarding both its diagnosis and treatment.
Mohamed Atef Behery, Eman Anwar Hasan, Eman Ahmed Ali, Ahmed Abdelkader Eltabakh   +3 more
doaj   +1 more source

The costs of reproduction in plants.

New Phytologist, 2002
This review reports on the processes associated with costs of reproduction, including some theoretical considerations, definitions and methodological aspects, followed by a list of the situations where costs are difficult to find. Despite some exceptions,
J. Obeso
semanticscholar   +1 more source

Comprehensive profiling of lncRNAs and mRNAs enriched in small extracellular vesicles for early noninvasive detection of colorectal cancer: diagnostic panel assembly and extensive validation

Molecular Oncology, EarlyView.
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova, Marketa Pavlikova, Lucie Pifkova, Robin Jugas, Tana Machackova, Lenka Radova, Milana Sachlova, Renata Bartosova, Tetiana Samoilenko, Zuzana Feckova, Jana Orlickova, Erika Slamova, Elleni Ponechal Michu, Dagmar Al Tukmachi, Michaela Ruckova, Martina Vodinska, Jan Kotoucek, Tina Catela Ivkovic, Marie Boudna, Lucia Bohovicova, Teodor Stanek, Jana Halamkova, Martin Svoboda, Vladimir Prochazka, Tomas Grolich, Zdenek Kala, Ondrej Slaby   +26 more
wiley   +1 more source

UGT2B17 genotype and the pharmacokinetic serum profile of Testosterone during substitution therapy with Testosterone Undecanoate. A retrospective experience from 207 men with hypogonadism.

Frontiers in Endocrinology, 2013
BackgroundTestosterone (T) is mainly excreted in the urine as testosterone glucuronide (TG). This glucuronidation is partly dependent on the UGT2B17 genotype, and TG excretion is therefore lower in men having the UGT2B17 deletion.
Anne Kirstine eBang, Niels eJørgensen, Ewa eRajpert-De Meyts, Anders eJuul   +3 more
doaj   +1 more source

XLV.—On the hydroid Lar sabellarum, gosse, and its reproduction [PDF]

, 1872
Thomas Hincks
openalex   +1 more source