Results 111 to 120 of about 1,070,079 (313)

Influenza and non-influenza ARVI in children. A relationship between cytokine profile, parameters of the “lipid peroxidation – antioxidant defense system” as well as clinical and laboratory indicators

Инфекция и иммунитет
Influenza and acute respiratory viral infections (ARVI) impose a substantial damage to the population health in the Russian Federation due to their seasonal circulation and predominantly affect young children. A very few data on the cytokine profile, the
Marina A. Darenskaya, E. D. Kazantseva, A. G. Petrova, L. V. Rychkova, S. I. Kolesnikov, N. V. Semenova, N. A. Kurashova, A. S. Lesnaya, L. F. Sholokhov, L. I. Kolesnikova   +9 more
doaj   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Legal Form, Commodities and Reproduction: Reading Pashukanis [PDF]

, 2013
This chapter offers a feminist reading of Pashukanis’s legal theory as a contribution to critical evaluation of the relationship between legality, commodification and gender. Contemporary feminist interests in the relationship between legal and non-legal
FLETCHER, R
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Parvovirus B19 Infection in Pregnancy—Course of the Disease, Fetal Complications and Management Tools: A Case Series and Literature Review

Children
Parvovirus B19 is a virus that causes a common and usually harmless infection in both children and adults. If the virus is transmitted transplacentally during pregnancy, it can have serious consequences for both the pregnant woman and the fetus ...
Olga Olejniczak, Jakub Kornacki, Daniel Boroń, Paweł Gutaj, Rafał Iciek, Ewa Wender-Ożegowska   +5 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Childlessness and the concentration of reproduction in Austria [PDF]

In this paper we study the changes of reproduction concentration among women, the levels of childlessness, individual factors influencing childlessness, and the contribution of childlessness to the concentration of reproduction in Austria for the female ...
Martin Spielauer
core  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Expressions of Insulin-Like Growth Factor-Binding Proteins (IGFBP) in Mare Endometrium during Estrous Cycle and Early Pregnancy. [PDF]

, 2010
43rd Annual Meeting of the Society-for-the-Study-of-Reproduction -- JUL 31-AUG 03, 2010 -- Milwaukee, WI[Abtract Not Available]Soc Study ...
Guzeloglu, Aydin, Atli, Mehmet O., Arslan, Selim, Celik, Sefa, Kayis, Seyit A., Semacan, Ahmet, Kurar, Ercan   +6 more
core   +2 more sources

Supportive Intervention for Unmet Needs Among Breast Cancer Patients and Their Spousal Caregivers: A Randomized Controlled Trial

Breast Cancer: Targets and Therapy
Qian Zhang,1,* Shan Wang,1,* Jiajia Zhang,1 Tianyu Chu,1 Xian Chen,1 Linlin Ma,1 Hui Zhou,1 Yibo Wu,1 Dewu Xu,2 Kai Jiang3 1Obstetrics, Gynecology and Reproduction Research Center, Affiliated Hospital of Jiangnan University, Wuxi, People ...
Zhang Q, Wang S, Zhang J, Chu T, Chen X, Ma L, Zhou H, Wu Y, Xu D, Jiang K   +9 more
doaj