Results 101 to 110 of about 1,070,079 (313)

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Reproduction Trends and the Emergence of Moral Panic [PDF]

, 1987
Are we witnessing a moral panic or a moral evaluation in the responses to the new reproductive technologies? Locating women in reproductive technology is a particularly powerful way into a discussion of values and consequences, intended or unintended ...
Hanmer, Jalna
core   +1 more source

Comparison Between Radiographic Vertebral Left Atrial Size (VLAS) and Echocardiographic Methods for Predicting Left Atrial Remodeling in Dogs With Mitral Valve Disease

Veterinary Medicine International
Conclusions and Clinics Relevance: VLAS has a positive relationship and important correlation with the echocardiographic variables and MINE score. Associated with its higher accessibility in clinical routine is a potential diagnostic method to detect ...
Natália Babolim Pereira, Guilherme Andraus Bispo, Maurício Peres Carneiro, Ricardo de Souza Buzo, Daniela Ribas Jané, Laís Calazans Menescal Linhares, Paulo Sergio Patto dos Santos, Luciana Del Rio Pinoti, Wagner Luis Ferreira   +8 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

replication-package-crash-reproduction-study.zip [PDF]

Replication package for crash reproduction study. (Unzip with 7z on Windows if builtin zip utility doesn't work.)
M A (13993116)
core   +1 more source

Intrinsic and extrinsic factors that influence ovarian environment and efficiency of reproduction in cattle [PDF]

, 2017
The emergent concepts on ovary environment, reproductive physiology and the development of pharmacology are constantly supporting the advance of assisted reproduction.
Baruselli, Pietro Sampaio, Vieira, Lais Mendes, Gimenes, Lindsay Unno [UNESP], Batista, Emiliana Oliveira Santana, Sales, José Nélio de Sousa, Ferreira, Roberta Machado   +5 more
core   +1 more source

The incidence and outcomes of perinatal asphyxia in spontaneous extreme preterm birth: a retrospective cohort study

Journal of Perinatal Medicine
To determine the incidence and outcome of perinatal asphyxia (PA) in spontaneous extreme preterm birth (PTB) between 24 and 28 weeks gestation.
Faiz Zohal, van ’t Hof Eline, de Boer Marjon, de Haan Timo R., Weissenbruch Mirjam, Klautz Arthur, Lippes Pien, Mol Ben Willem, de Groot Christianne, Bakker Petra   +9 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

A quantitative analysis of signal reproduction from cylinder recordings measured via noncontact full surface mapping [PDF]

, 2008
Sound reproduction via a noncontact surface mapping technique has great potential for sound archives, aiming to digitize content from early sound recordings such as wax cylinders, which may otherwise be “unplayable” with a stylus.
Nascè, Antony, Antony Nascè, Peter J. Boltryk, Boltryk, Peter, Hill, Martyn, John W. McBride, McBride, John W., Martyn Hill   +7 more
core   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source