Results 81 to 90 of about 1,255,722 (301)
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
High-fidelity colour reproduction for high-dynamic-range imaging [PDF]
, 2010 The aim of this thesis is to develop a colour reproduction system for high-dynamic-range (HDR) imaging. Classical colour reproduction systems fail to reproduce HDR images because current characterisation methods and colour appearance models fail to ...
Kim, M.H.
core
Reducing bias in auditory duration reproduction by integrating the reproduced signal [PDF]
, 2013 Duration estimation is known to be far from veridical and to differ for sensory estimates and motor reproduction. To investigate how these differential estimates are integrated for estimating or reproducing a duration and to examine sensorimotor biases ...
Müller Hermann J. +11 more
core +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
The effect of brucellosis on women’s health and reproduction
, 2015 Due to its potential harmful effects on the general health and reproductive life of the women, in the light of available literature, it was aimed to review the effect of human brucellosis on women's health and reproduction. Data from 75 reports belonging
Kurdoglu, Z. +7 more
core +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Âl Hallingdal Door Reproduction
, 1880 Detail, showing the carving at the top of the portal opening; The original object is from the Church of Âl, in Hallingdal, now in the Universitetets Oldsaksamling, Oslo, Norway, is wood and dates from ca. 1150-1175.
after unknown (Norse sculptor) +1 more
core
Depletion and social reproduction [PDF]
, 2011 Much work has been done on the unaccounted contribution of social reproductive work to national economies. What has been less studied is the consequence of this neglect for individuals, households and communities engaged in social reproduction.
Thomas, Dania +2 more
core
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
ASSISTED HUMAN REPRODUCTION: PSYCHOLOGICAL AND ETHICAL DILEMMAS
, 2003 Contributors -- Foreword / Professor Susan Golombok -- Introduction -- Ch. 1. Assisted human reproduction: contemporary policy and practice in the UK / Eric Blytb, Nina Martin and Claire Potter -- Ch. 2. Issues of gamete donation and sex selection: a
core