Results 71 to 80 of about 1,255,722 (301)

Is ‘Assisted Reproduction’ Reproduction? [PDF]

open access: yesThe Philosophical Quarterly, 2017
Abstract With an increasing number of ways to ‘assist’ reproduction, some bioethicists have started to wonder what it takes to become a genetic parent. It is widely agreed that sharing genes is not enough to substantiate the parent–offspring relation, but what is? Without a better understanding of the concept of reproduction (and what it
openaire   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Feminist Reflections on the Scope of Labour Law: Domestic Work, Social Reproduction and Jurisdiction [PDF]

open access: yes, 2014
Drawing on feminist labour law and political economy literature, I argue that it is crucial to interrogate the personal and territorial scope of labour.
Judy Fudge, Fudge, Judy
core   +1 more source

A Health Literate Healthcare Organization Index System for China: Based on CiteSpace and Qualitative Analysis

open access: yesJournal of Multidisciplinary Healthcare
Shenyu Zhao,1,* Yang Chen,2,* Xiyang Xia,2 Jing Zhou,2 Xiaoyu Wang,2 Qing Sun,1 Jiaqian Chang,2 Jiaying Ge,2 Lingmin Hu,2 Renjie Lu1,3 1Changzhou Third People’s Hospital, Changzhou Medical Center, Nanjing Medical University, Changzhou ...
Zhao S   +9 more
doaj  

In rats with estradiol valerate-induced polycystic ovary syndrome, the acute blockade of ovarian β-adrenoreceptors improve ovulation

open access: yesReproductive Biology and Endocrinology, 2019
Background Polycystic ovary syndrome is characterized by hyperactivity of the ovarian sympathetic nervous system, increases in the content and release of norepinephrine, as well as decreases in the number of β-adrenoreceptors.
Berenice Venegas   +6 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The net reproduction rate and the type-reproduction number in multiregional demography [PDF]

open access: yes
In order to study effects of migration on demographic changes of multiregional populations, multiregional population modelling is a useful traditional tool.
Hisashi Inaba
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Effects of vaginal vs oral progesterone supplementation before embryo transfer on live birth rates and levels: a randomized trial

open access: yesReproduction and Fertility
The increase in frozen embryo transfers (FETs) is a consequence of advances in embryo vitrification and the implementation of genetic screening of embryos.
Gorka Barrenetxea   +8 more
doaj   +1 more source

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