ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Heat Stress as a Barrier to Successful Reproduction and Potential Alleviation Strategies in Cattle
In recent decades, the adverse effects of global warming on all living beings have been unanimously recognized across the world. A high environmental temperature that increases the respiration and rectal temperature of cattle is called heat stress (HS ...
Il-Keun Kong +5 more
core +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
The effect of brucellosis on women’s health and reproduction
Due to its potential harmful effects on the general health and reproductive life of the women, in the light of available literature, it was aimed to review the effect of human brucellosis on women's health and reproduction. Data from 75 reports belonging
Kurdoglu, Z. +7 more
core +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Abstracts of the communications presented during the 8th French Rabbits Days.Paris, June 9-10th, 1999: GENETICS - REPRODUCTION [PDF]
World Rabbit Science (1999). Abstracts of the communications presented during the 8th French Rabbits Days.Paris, June 9-10th, 1999: GENETICS - REPRODUCTION. World Rabbit Science. 07.
World Rabbit Science +1 more
core +1 more source
SEROLOGICAL INVESTIGATION ON SPREADING OF BRUCELIOSIS , CHLAMYDIOSIS AND LEPTOSPIROSIS IN FARM ANIMALS [PDF]
Three thousands and two hundred seventy one blood sera (2663 from cattle, 558 from buffaloes, and 50 from horses) were tested for antibodies against Brucella abortus, Chlamydia psittaci and Leptospira serovars.
E.R. H ATTIA +3 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Potential Importance of Circulating anti-Müllerian Hormone as a Predictor of Superovulatory Response in Dairy Holstein Cows [PDF]
Plasma anti-Müllerian hormone concentration (AMH) in cows is a useful endocrine marker for ovarian response to gonadotropin superstimulation. Here, we investigated the possible relationship between AMH concentration measured in plasma and superovulatory ...
Ebtihal Ibrahim +2 more
doaj +1 more source

