Results 31 to 40 of about 679,548 (318)
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
VIROLOGICAL AND PATHOLOGICAL STUDIES ON BUFFALO POX VIRUS ISOLATED FROM DAIRY BUFFALOES UDDER [PDF]
Veterinary Medical Journal - Giza, 2005 Pox like lesions were frequently recorded in 43.75% dairy buffaloes recently introduced into small and moderate dairy barns at Kafr EL-Gabal and Zawet Abo Mesalem districts at Giza Governorate. These affections led to reduction of milk yield.
S SELIM +2 more
doaj +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Endocannabinoids and Reproduction [PDF]
International Journal of Endocrinology, 2014 Infertility is a worldwide reproductive health problem whose consequences have deep psychological and social impact in health, demographic change, and wellbeing. Thus, the knowledge of basic, conserved modulators of reproduction might contribute to the discovery of new potential target for the exploitation of drugs to treat infertility in humans ...
Rosaria Meccariello +3 more
openaire +4 more sources
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
EFFECT OF OXYTETRACYCLINE ON IMMUNOCOMPETENT DAIRY GOAT [PDF]
Veterinary Medical Journal - Giza, 2005 Dairy goats treated with oxytetracycline revealed a significant reduction in lymphocyte transformation which occurred 3 days post treatment and lasted for 4 weeks.
A ABDEL-AAL, H HASSAN, HANAA ALAM
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
EFFECT OF PRECOOLING INCUBATION TIME ON THE EFFICIENCY OF ADDED ANTIBIOTICS ON TOTAL BACTERIAL COUNT AND VIABILITY OF FROZEN RAM SEMEN [PDF]
Assiut Veterinary Medical Journal, 2008 A total of 16 pooled raw ram semen samples were collected from healthy rams cross bread (Rahmani & Barki). Semen samples of at least 70% initial sperm motility and 3000x106 sperm/ml were used.
R.H. OSMAN +2 more
doaj +1 more source