Results 51 to 60 of about 5,005,502 (303)

Bifurcation analysis and optimal control of a network-based SIR model with the impact of medical resources

Nonlinear Analysis, 2023
A new network-based SIR epidemic model, which incorporates the individual medical resource factor and public medical resource factor is proposed. It is verified that the larger the public medical resource factor, the smaller the control reproduction ...
Fang Wang, Maoxing Liu, Lei Zhang, Boli Xie   +3 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

A Putative Transcription Factor pcs1 Positively Regulates Both Conidiation and Sexual Reproduction in the Cereal Pathogen Fusarium graminearum

The Plant Pathology Journal, 2014
The plant pathogen Fusarium graminearum causes Fusarium head blight in cereal crops and produces mycotoxins that are harmful to animals and humans. For the initiation and spread of disease, asexual and sexual reproduction is required.
Boknam Jung, Jungwook Park, Hokyoung Son, Yin-Won Lee, Young-Su Seo, Jungkwan Lee   +5 more
doaj   +1 more source

Female Reproductive Factors and Differentiated Thyroid Cancer [PDF]

Frontiers in Endocrinology, 2017
Differentiated thyroid cancer (DTC) is markedly more common in women than men, the highest female-to-male ratio being recorded during the reproductive period. This evidence has led to the suggestion that female hormonal and reproductive factors may account for the observed DTC gender disparity. This review focuses on current evidence on the risk of DTC
Moleti, Mariacarla, Sturniolo, Giacomo, Di Mauro, Maria, Russo, Marco, Vermiglio, Francesco   +4 more
openaire   +4 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Growth and defense enzyme responses of grafted cucurbit crops to varying initial populations of Meloidogyne incognita

Journal of Nematology
Root-knot nematode (Meloidogyne incognita) is among the most serious constraints to cucurbit crop production worldwide. This study evaluated the effects of different initial population densities (0, 1,000, 2,000, 4,000, and 8,000 second-stage juveniles ...
Kesba Hosny H., EL-Ganainy Sherif M., Hassnin Nourhan M. M., Ali Ali H. H.   +3 more
doaj   +1 more source

Reaction of soybean cultivars to Meloidogyne javanica and Meloidogyne incognita

Revista Ceres
Nematodes of the genus Meloidogyne are associated with soybean cultivation, unknown the reaction of cultivars. The objective of this work was to determine the reaction of soybean cultivars to M. javanica and M. incognita.
Valéria Cecília Ghissi Mazzetti, Gustavo Luiz Visintin, Igor Pirez Valério, Juliane Nicolodi Camera, Carolina Cardoso Deuner, Pedro Luiz Martins Soares   +5 more
doaj   +1 more source

Biological services by Streptomyces lavendulae MTCC 706 to control invasion, development and reproduction of root-knot nematode (Meloidogyne incognita) infecting tomato cv Pusa Ruby

The Indian Journal of Agricultural Sciences, 2016
The drench application of S. lavendulae MTCC706 @ 2% v/w (SLT) resulted in less than 50% juvenile invasion of M. incognita J2s in tomato (cv. Pusa Ruby), delayed development of J4s, 50.7% reduction in root galling and 42.7% reduction in egg mass ...
C SELLAPERUMAL, ANJU KAMRA, D K SHARMA
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source