Results 101 to 110 of about 6,869,135 (344)
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
In most ant species with flightless queens, such as the genus Proformica Ruzsky, 1902, winged males are crucial for allowing proper gene flow between and within populations. Furthermore, since these taxa often have a complex taxonomy, it is all the more
Lorenzo Fraysse, Christophe Galkowski
doaj +1 more source
The role of histone modifications in transcription regulation upon DNA damage
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
The Animal Sexes as Historical Explanatory Kinds [PDF]
Though biologists identify individuals as ‘male’ or ‘female’ across a broad range of animal species, the particular traits exhibited by males and females can vary tremendously.
Franklin-Hall, Laura
core +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Social-economic determinants of women’s reproductive health in Almaty (Kazakhstan)
In the Almaty metropolitan area with the significant social-economic stratification, the relevance of the study is determined by the need to understand how household income affects women’s reproductive strategies and identity.
A. A. Bakytzhanova +2 more
doaj +1 more source
Premarital Sex Among Adolescent Street Children in Pekanbaru [PDF]
Premarital sex is any behavior that is driven by sexual desire with the opposite sex before marriage. Some premarital sex activities include feeling, kissing, necking, petting, and intercourse.
Alamsyah, A. (Agus) +2 more
core
Mechanisms of parasite‐mediated disruption of brain vessels
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
The impact of Western values on marital, family, and reproductive attitudes of youth
The complex impact of Western values on marital, family, and reproductive attitudes transformation in Russian youth in the context of globalization, digitalization, and an ideologically multipolar world has been studied.
F. G. Myshko, V. V. Popov
doaj +1 more source

