Results 161 to 170 of about 6,869,135 (344)
Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer
Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov +10 morewiley +1 more sourceIntegrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar +13 morewiley +1 more sourceYAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna +9 morewiley +1 more sourceMigration and first-time parenthood [PDF]
This article investigates the reproductive behavior of young women and men in the post-Soviet Central Asian republic of Kyrgyzstan, focusing on the link between migration and fertility.Gunnar Andersson, Lesia Nedoluzhkocore Genome-wide analysis identifies 12 loci influencing human reproductive behavior
Nature Genetics, 2016 Nicola Barban, R. Jansen, R. Vlaming, Ahmad Vaez, Ahmad Vaez, Jornt J. Mandemakers, Felix C. Tropf, Xia Shen, Xia Shen, James F. Wilson, D. Chasman, I. Nolte, V. Tragante, S. W. Laan, J. Perry, Augustine Kong, Augustine Kong, T. Ahluwalia, T. Ahluwalia, E. Albrecht, L. Yerges-Armstrong, G. Atzmon, G. Atzmon, K. Auro, K. Auro, K. Ayers, A. Bakshi, D. Ben-Avraham, K. Berger, A. Bergman, L. Bertram, L. Bertram, L. Bielak, G. Bjornsdottir, M. Bonder, L. Broer, M. Bui, C. Barbieri, A. Cavadino, A. Cavadino, J. Chavarro, Constance Turman, M. P. Concas, H. Cordell, G. Davies, P. Eibich, N. Eriksson, T. Esko, T. Esko, J. Eriksson, F. Falahi, J. Felix, M. Fontana, L. Franke, I. Gandin, A. Gaskins, C. Gieger, E. Gunderson, Xiuqing Guo, C. Hayward, Chunyan He, E. Hofer, Hongyan Huang, Peter K. Joshi, S. Kanoni, R. Karlsson, S. Kiechl, A. Kifley, A. Kluttig, P. Kraft, V. Lagou, C. Lecoeur, J. Lahti, R. Li-Gao, P. Lind, Tian Liu, E. Makalic, Crysovalanto Mamasoula, Lindsay K. Matteson, H. Mbarek, P. McArdle, George Mcmahon, S. Meddens, S. Meddens, E. Mihailov, Michael B. Miller, S. Missmer, C. Monnereau, P. J. Most, Ronny Myhre, M. Nalls, T. Nutile, I. Kalafati, E. Porcu, I. Prokopenko, I. Prokopenko, K. Rajan, J. Rich-Edwards, C. A. Rietveld, A. Robino, L. Rose, R. Rueedi, R. Rueedi, K. Ryan, Y. Saba, D. Schmidt, Jennifer A. Smith, L. Stolk, E. Streeten, A. Tönjes, G. Thorleifsson, Sheila Ulivi, J. Wedenoja, J. Wellmann, P. Willeit, P. Willeit, P. Willeit, Jie Yao, L. Yengo, Jinghua Zhao, Wei Zhao, D. Zhernakova, N. Amin, Howard Andrews, B. Balkau, N. Barzilai, S. Bergmann, S. Bergmann, G. Biino, H. Bisgaard, K. Bønnelykke, D. Boomsma, J. Buring, Harry Campbell, S. Cappellani, M. Ciullo, S. Cox, F. Cucca, D. Toniolo, G. Davey-Smith, I. Deary, G. Dedoussis, P. Deloukas, P. Deloukas, C. Duijn, E. D. Geus, J. Eriksson, Denis A. Evans, J. Faul, C. Sala, P. Froguel, Paolo Gasparini, G. Girotto, H. Grabe, K. Greiser, P. Groenen, H. G. D. Haan, J. Haerting, T. Harris, A. Heath, K. Heikkilä, A. Hofman, A. Hofman, G. Homuth, E. Holliday, J. Hopper, E. Hyppönen, E. Hyppönen, B. Jacobsson, B. Jacobsson, V. Jaddoe, M. Johannesson, A. Jugessur, M. Kähönen, E. Kajantie, E. Kajantie, E. Kajantie, S. Kardia, B. Keavney, B. Keavney, I. Kolčić, P. Koponen, Peter Kovacs, F. Kronenberg, Z. Kutalik, Z. Kutalik, Martina La Bianca, G. Lachance, W. Iacono, Sandra Lai, T. Lehtimäki, D. Liewald, C. Lindgren, Yongmei Liu, Robert Luben, M. Lucht, R. Luoto, P. Magnus, P. Magnusson, N. Martin, M. McGue, R. McQuillan, S. Medland, C. Meisinger, D. Mellström, A. Metspalu, M. Traglia, L. Milani, Paul A. Mitchell, G. Montgomery, G. Montgomery, D. Mook-Kanamori, D. Mook-Kanamori, R. Mutsert, E. Nøhr, C. Ohlsson, J. Olsen, Ken K. Ong, L. Paternoster, A. Pattie, B. Penninx, M. Perola, M. Perola, M. Perola, P. Peyser, M. Pirastu, O. Polašek, C. Power, J. Kaprio, J. Kaprio, L. Raffel, K. Räikkönen, O. Raitakari, P. Ridker, S. Ring, Kathryn Roll, I. Rudan, D. Ruggiero, D. Rujescu, V. Salomaa, D. Schlessinger, H. Schmidt, R. Schmidt, N. Schupf, J. Smit, R. Sorice, Timothy D. Spector, J. Starr, D. Stöckl, K. Strauch, M. Stumvoll, M. Swertz, U. Thorsteinsdóttir, U. Thorsteinsdóttir, R. Thurik, N. Timpson, J. Tung, A. Uitterlinden, S. Vaccargiu, J. Viikari, V. Vitart, H. Völzke, P. Vollenweider, D. Vuckovic, Johannes Waage, G. Wagner, Jie-Jin Wang, N. Wareham, D. Weir, G. Willemsen, J. Willeit, A. Wright, K. Zondervan, K. Stefánsson, K. Stefánsson, R. Krueger, James J. Lee, Daniel J. Benjamin, Daniel J. Benjamin, D. Cesarini, P. Koellinger, P. Koellinger, M. Hoed, H. Snieder, M. Mills +284 moresemanticscholar +1 more sourceEmerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger +3 morewiley +1 more sourceA Predictive Model for Determinants of Reproductive Behaviour in Şanlıurfa
Hemşirelikte Araştırma Geliştirme DergisiAim: This study aims to predict the determinants of current and future reproductive behaviour in Şanlıurfa.Material and Method: A cross-sectional study was conducted with 385 married women to examine the determinants of reproductive behavior.Ayşe Taştekin, Şehadet Taşkındoaj
