Results 151 to 160 of about 287,216 (309)

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Reproductive contributions of Taiwan´s foreign wives from the top five source countries [PDF]

This research studies the reproductive contributions of Taiwan’s foreign wives from China, Vietnam, Indonesia, Thailand, and the Philippines, based on applications of the multinomial logit model to the micro data of the 2003 Census of Foreign Spouses ...
Kao-Lee Liaw, Lin Ji-Ping, Chien-Chia Liu   +2 more
core  

Deletion of neural estrogen receptor alpha induces sex differential effects on reproductive behavior in mice. [PDF]

Commun Biol, 2022
Trouillet AC, Ducroq S, Naulé L, Capela D, Parmentier C, Radovick S, Hardin-Pouzet H, Mhaouty-Kodja S.   +7 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Reproductive history and mortality later in life: a comparative study of England & Wales and Austria [PDF]

Does a woman’s reproductive history influence her life span? This study explores the question on the basis of data from two contemporary female populations: England & Wales and Austria. It is the first comparative study that investigates the relationship
Gabriele Doblhammer
core  

A Predictive Model for Determinants of Reproductive Behaviour in Şanlıurfa

Hemşirelikte Araştırma Geliştirme Dergisi
Aim: This study aims to predict the determinants of current and future reproductive behaviour in Şanlıurfa.Material and Method: A cross-sectional study was conducted with 385 married women to examine the determinants of reproductive behavior.
Ayşe Taştekin, Şehadet Taşkın
doaj  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Work hard, play hard: how sexually differentiated microglia work to shape social play and reproductive behavior. [PDF]

Front Behav Neurosci, 2022
Sullivan O, Ciernia AV.
europepmc   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Hox genes regulate asexual reproductive behavior and tissue segmentation in adult animals. [PDF]

Nat Commun, 2021
Arnold CP, Lozano AM, Mann FG, Nowotarski SH, Haug JO, Lange JJ, Seidel CW, Alvarado AS.   +7 more
europepmc   +1 more source