Results 151 to 160 of about 4,526,563 (255)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

The Neuroendocrine Regulation of Reproductive Behavior and Emotional Control by Kisspeptin. [PDF]

J Clin Endocrinol Metab
Mills EG, Tsoutsouki J, Pierret ACS, Comninos AN, Dhillo WS.   +4 more
europepmc   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Mendelian randomization study on the causal link between reproductive behavior and postpartum depression. [PDF]

Medicine (Baltimore)
Zou J, Li C, Ma H, Zhang Y.
europepmc   +1 more source

Analysis of cell-type-specific chromatin modifications and gene expression in Drosophila neurons that direct reproductive behavior. [PDF]

PLoS Genet, 2021
Palmateer CM, Moseley SC, Ray S, Brovero SG, Arbeitman MN.   +4 more
europepmc   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Dietary Spirulina (<i>Arthrospira platensis</i>) Modulates Survival, Growth, Reproductive Behavior, and Spawning Performance in Zebrafish, <i>Danio rerio</i>. [PDF]

Animals (Basel)
Flagiello F, Raggio M, Diano M, Esposito S, Parente M, Attanasio C, De Felice E, Lucini C, Mazzoleni S, de Girolamo P, D'Angelo L, Palladino A.   +11 more
europepmc   +1 more source

Juvenile hormone pathway in honey bee larvae: A source of possible signal molecules for the reproductive behavior of Varroa destructor. [PDF]

Ecol Evol, 2021
Aurori CM, Giurgiu AI, Conlon BH, Kastally C, Dezmirean DS, Routtu J, Aurori A.   +6 more
europepmc   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Food sensing controls <i>C. elegans</i> reproductive behavior by neuromodulatory disinhibition. [PDF]

Sci Adv
Chen YC, Zang KE, Ahamed H, Ringstad N.
europepmc   +1 more source