Results 161 to 170 of about 656,990 (357)

Deletion of neural estrogen receptor alpha induces sex differential effects on reproductive behavior in mice. [PDF]

Commun Biol, 2022
Trouillet AC, Ducroq S, Naulé L, Capela D, Parmentier C, Radovick S, Hardin-Pouzet H, Mhaouty-Kodja S.   +7 more
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Work hard, play hard: how sexually differentiated microglia work to shape social play and reproductive behavior. [PDF]

Front Behav Neurosci, 2022
Sullivan O, Ciernia AV.
europepmc   +1 more source

Neuroanatomical substrates of reproductive behavior in male sunfish (Genus Lepomis) [PDF]

, 1978
Leo S. Demski
openalex   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

A Predictive Model for Determinants of Reproductive Behaviour in Şanlıurfa

Hemşirelikte Araştırma Geliştirme Dergisi
Aim: This study aims to predict the determinants of current and future reproductive behaviour in Şanlıurfa.Material and Method: A cross-sectional study was conducted with 385 married women to examine the determinants of reproductive behavior.
Ayşe Taştekin, Şehadet Taşkın
doaj  

The effects of phytosterols on the sexual behavior and reproductive function in the Japanese quail (Coturnix coturnix japonica)

, 2017
Mohammad Ibrahim Qasimi, Kentaro Nagaoka, Gen Watanabe   +2 more
openalex   +1 more source

Internet Use and Fertility Behavior Among Reproductive-Age Women in China

, 2022
Peng Nie, Peng Xu, Tianyuan Luo
openalex   +1 more source

Formation of Reproductive Behavior of Student Youth in the Process of Studying the Humanities [PDF]

, 2021
Nigora Mamayusufovna Kenjaboeva
openalex   +1 more source