Results 71 to 80 of about 287,216 (309)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Divergent evolution of male aggressive behaviour : another reproductive isolation barrier in extremophile poeciliid fishes? [PDF]

, 2011
Reproductive isolation among locally adapted populations may arise when immigrants from foreign habitats are selected against via natural or (inter-)sexual selection (female mate choice).
Riesch, Rüdiger, Sassmannshausen, Vanessa, Schlupp, Ingo, Klein, Moritz, Plath, Martin, Bierbach, David, Parzefall, Jakob   +6 more
core   +1 more source

Relationship between reproductive health literacy and components of healthy fertility in women of the reproductive age

Journal of Education and Health Promotion
BACKGROUND AND AIM: One of the key factors affecting women’s behavior with fertility issues is their health literacy, but this topic has been less addressed in the existing studies.
Batool Ghavami, Zahra Sohrabi, Ziba RaisiDehkordi, Fatemeh Mohammadi   +3 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Effect of Feathers as Nest Insulation on Incubation Behavior and Reproductive Performance of Tree Swallows (\u3cem\u3eTachycineta bicolor\u3c/em\u3e)

, 1995
Many species of birds line their nests with feathers, presumably because of the insulative qualities of feathers and because feathers may act as a barrier between nest parasites and nestlings.
Faro, Christine A, Bosman, Ruth M, Houtteman, Stephen G, Kluisza, Timothy S, Lombardo, Michael P   +4 more
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Examining the predictive value of fertility preferences among Ghanaian women [PDF]

Despite extensive research, doubts remain regarding the degree of correspondence between prior stated fertility preferences and subsequent fertility behavior. Preference instability is a factor that potentially undermines predictiveness.
John Casterline, David Johnson, Ivy Kodzi   +2 more
core  

Kenya: Communities support adolescent reproductive health education

, 2003
Young people in Kenya have limited knowledge of reproductive health (RH) and face many challenges in their transition to adulthood. Chief among these challenges is the high prevalence of HIV/AIDS among adults and its increasing incidence among rural ...
Frontiers in Reproductive Health
core   +1 more source

Demographic Problems in the Northern Regions of the Republic of Kazakhstan

Экономика: стратегия и практика
This article aims to analyse demographic and migration processes in Kazakhstan, focusing on identifying their impact on society’s economic, political and social aspects.
K. Bodaukhan, N. Shaikenova, A. Shilmanova, M. Bayandin, Zh. Kochiygit   +4 more
doaj   +1 more source