Results 171 to 180 of about 1,879,235 (344)

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Floral Characteristics and Reproductive Biology in Brazilian Melon Accessions: Insights from Commercial and Exotic Varieties. [PDF]

open access: yesPlants (Basel)
Sanabria-Verón NC   +5 more
europepmc   +1 more source

Reproductive Biology of ‘Ataulfo’ Mango: The State of the Art and Challenges for Improving Pollination and Fruit Production

open access: hybrid
Rodrigo Lucas‐García   +5 more
openalex   +2 more sources

Activins in reproductive biology and beyond.

open access: yesHuman Reproduction Update, 2016
R. Wijayarathna   +2 more
semanticscholar   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

New genomic resources to boost research in reproductive biology to enable cost-effective hybrid seed production. [PDF]

open access: yesPlant Genome
Rohde A   +16 more
europepmc   +1 more source

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