Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Small non-coding RNAs have predicted roles in reproductive biology and transposable element regulation in the parasitic worm Strongyloides venezuelensis. [PDF]
Lastik D +7 more
europepmc +2 more sources
Reproductive Biology of the Crocodylia
Grahame Webb, Charlie Manolis
doaj
Effects of Pharmaceuticals and Endocrine-Disrupting Chemicals on Reproductive Biology of Aquatic Fauna: Penguins as Sentinel Species. [PDF]
Okuthe GE, Dube E, Mafunda PS.
europepmc +1 more source
New horizons in the reproductive biology of Chinese pangolin (Manis pentadactyla) using the gonadal hormonal profile. [PDF]
Arora B, Pei KJ, Chin SC.
europepmc +1 more source
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Knowing the reproductive biology and reproductive success of Scrophularia oxyrhyncha Coincy as a first step for its conservation. [PDF]
Rodríguez-Riaño T +6 more
europepmc +1 more source
Reproductive Biology and Breeding Systems of Two Opisthopappus Endemic and Endangered Species on the Taihang Mountains. [PDF]
Wang Y +6 more
europepmc +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source

