Results 211 to 220 of about 2,335,827 (339)

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Reproductive biology of female common dolphins (Delphinus delphis) in New Zealand waters. [PDF]

open access: yesMar Biol, 2022
Palmer EI   +5 more
europepmc   +1 more source

Sirtuins in gamete biology and reproductive physiology: emerging roles and therapeutic potential in female and male infertility.

open access: yesHuman Reproduction Update, 2018
C. Tatone   +6 more
semanticscholar   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Solar radiation, temperature and the reproductive biology of the coral Lobactis scutaria in a changing climate. [PDF]

open access: yesSci Rep, 2023
Bouwmeester J   +6 more
europepmc   +1 more source

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