Results 61 to 70 of about 286,307 (262)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Seminal per- and polyfluoroalkyl substance exposure and sperm quality impairment: from toxic target to rescue

Environment International
The link between per- and polyfluoroalkyl substances (PFAS) and impaired sperm quality has been disputable, partially attributed to the relatively small sample size and the lack of knowledge on exposure status in the microenvironment of target site. Here,
Lan Shi, Lin Tao, Yating Zong, Chang Gao, Bing Han, Tianrui Gao, Chenghui Huang, Bingjie Liu, Huan Wu, Dongdong Tang, Yajing Liu, Hua Wang, De-Xiang Xu, Yunxia Cao, Yichao Huang, Xiaojin He   +15 more
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Ciclo reproductivo del molusco Atrina maura (Pterioidea: Pinnidae) en un sistema lagunar costero, al sur del Pacífico tropical mexicano

Revista de Biología Tropical, 2007
De febrero de 1997 a febrero de 1998, se recolectaron mensualmente muestras aleatorias del molusco Atrina maura en el sistema lagunar Corralero-Alotengo, Oaxaca, México.
Claudia Angel-Pérez, Saúl J Serrano-Guzmán, Miguel Angel Ahumada-Sempoal   +2 more
doaj  

Monitoring the phenology of Myrcianthes pungens (O. Berg) d. Legrand in the state of Rio Grande do Sul - Brazil

Revista Brasileira de Fruticultura
Guabiju (Mycianthes pungens (O. Berg) Legrand) is a fruit tree with great potential for commercial exploitation due to its nutritional characteristics. The aim of this work was to study the reproductive cycle of M.
Pedro Augusto Veit, Sergio Francisco Schwarz, Divanilde Guerra   +2 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Case Report: Two clinical cases of severe deep infiltrating endometriosis with infertility—transplantation first or surgery first? Natural cycle or artificial cycle?

Frontiers in Medicine
Deep infiltrating endometriosis (DIE) is a severe condition frequently linked to infertility, yet the optimal integration of surgery and assisted reproductive technology (ART) remains controversial.
Fei Tang, Fei Tang, Fei Tang, Ye He, Ye He, Ye He, Peipei Guo, Peipei Guo, Peipei Guo, Yue Wang, Yue Wang, Yue Wang, Yunyun Liu, Yunyun Liu, Yunyun Liu, Liting Wang, Liting Wang, Liting Wang, Yi Wang, Yi Wang, Yi Wang, Pengxiang Xie, Pengxiang Xie, Pengxiang Xie, Youyan Fang, Youyan Fang, Youyan Fang, Caihua Li, Caihua Li, Caihua Li, Zhaojuan Yu, Zhaojuan Yu, Zhaojuan Yu, Xuqing Li, Xuqing Li, Xuqing Li, Zhaolian Wei, Zhaolian Wei, Zhaolian Wei   +38 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Reproductive biology of the endangered percid Zingel asper in captivity: a histological description of the male reproductive cycle

Folia Histochemica et Cytobiologica, 2011
The endemic Rhodanian percid Zingel asper (Linnaeus, 1758), is usually found throughout the Rhônebasin, but this fish is now in sharp decline. Understanding its reproductive physiology is important so as to be ableto artificially control its reproduction
Christine Chevalier, Christine de Conto, Jean-Marie Exbrayat   +2 more
doaj