Results 61 to 70 of about 2,793,995 (298)

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Successful Birth Following Transfer of Frozen-Thawed Embryos Produced from in-Vitro Matured Oocytes

, 2010
It is well established that ovarian hyperstimulation syndrome (OHSS) is more frequent in patients with polycystic ovarian syndrome. In-vitro maturation (IVM) of immature oocytes presents a potential alternative for the fertility treatment and prevention ...
Guven, Suleyman, Demirol, Aygul, Gurgan, Timur, Sari, Tamer, Benkhalifa, Moncef, Timur Gurgan, Suleyman Guven, Tamer Sari, Moncef Benkhalifa, Aygul Demirol   +9 more
core   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Histological feature of ovarian structures throughout the reproductive cycle in alpine goats (Capra hircus)

Macedonian Veterinary Review, 2019
The knowledge about ovarian physiology in small ruminants is still limited, especially when compared to other domestic species. Ovarian function in goats is mainly assessed by ultrasonographic techniques, whereas a quali-quantitative feature of the ...
Debora Groppetti, Alessandro Pecile, Stefano Frattini, Giulio Pagnacco, Silvana Arrighi   +4 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

The Reproductive Cycle of the Raccoon in Illinois [PDF]

, 1973
The objectives of this study were to gather data on the reproductive cycle and the basic anatomy of the reproductive system of the raccoon and to investigate those aspects of the raccoon\u27s reproductive physiology that gave promise of increasing our ...
Nalbandov, A. V., Sanderson, Glen C.
core   +1 more source

Reproductive cycle and population structure of the deep-water shrimp Aristeus antillensis A. Milne Edwards & Bouvier, 1909 (Decapoda: Aristeidae) on southeast Brazilian continental slope Ciclo reproductivo y estructura poblacional del camarón de aguas profundas Aristeus antillensis A. Milne Edwards & Bouvier, 1909 (Decapoda: Aristeidae) en el talud continental del sureste de Brasil

Latin American Journal of Aquatic Research, 2009
The "alistado shrimp" (Aristeus antillensis) is one of the targets of the trawling fleet operating since 2002 along the continental slope of the Brazilian Economic Exclusive Zone between 700 and 800 m depth.
Paulo Ricardo Pezzuto, Martín Coachman Dias   +1 more
doaj  

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source