Results 71 to 80 of about 289,865 (262)
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Chinese sleeper is an invasive species from South Asia inhabiting Eastern and Central Europe. So far, no detailed analysis of the reproductive cycle of Chinese sleepers has been conducted.
L. Kirczuk +5 more
doaj +1 more source
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Fixed-time artificial insemination technology in buffaloes: a review
Buffalo occupies a leading position as a major livestock commodity and is the primary milk-producing animal in many countries like Italy, China, India, Pakistan, Bangladesh, and Nepal. Buffalo farming emphasizes the significance of effective reproductive
Hubdar Ali Kolachi +12 more
doaj +1 more source
THE REPRODUCTIVE CYCLE OF SPHAERIUM SIMILE
1. Reproduction occurs throughout the year in S. simile although definite variations can be observed in different reproductive activities at different times. 2. Gametogenesis and mature gametes are visible to some extent during the fall, winter and early spring (particularly in specimens less than 12 mm long) but the production of gametes appears to be
openaire +3 more sources
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Canaries' Microbiota: The Gut Bacterial Communities along One Female Reproductive Cycle. [PDF]
Hattab J +4 more
europepmc +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
The gametogenesis and reproduction of the matrinxã, Brycon orthotaenia in the São Francisco river, Pirapora Region, Minas Gerais, were studied from December, 1998 to November, 1999. The matrinxã B.
T. L. Gonçalves +2 more
doaj +1 more source
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source

