Results 61 to 70 of about 2,415,924 (290)

Effects of Mustelid gammaherpesvirus 1 (MusGHV-1) Reactivation in European Badger (Meles meles) Genital Tracts on Reproductive Fitness

Pathogens, 2020
Reactivation of latent Gammaherpesvirus in the genital tract can lead to reproductive failure in domestic animals. Nevertheless, this pathophysiology has not received formal study in wild mammals. High prevalence of Mustelid gammaherpesvirus 1 (MusGHV-1)
Ming-shan Tsai, Ursula Fogarty, Andrew W. Byrne, James O’Keeffe, Chris Newman, David W. Macdonald, Christina D. Buesching   +6 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Peculiarities of Glis glis (Gliridae, Rodentia) monitoring in nest boxes on the eastern periphery of the range

Nature Conservation Research: Заповедная наука
Evaluation of the population dynamics of threatened species is one of the main purposes of Protected Areas. Regular monitoring of the Glis glis population using nest boxes has been conducted during eight years in the Zhiguli State Nature Biosphere ...
Victoria A. Vekhnik, Vladimir P. Vekhnik
doaj   +1 more source

Infectious Agents Associated with Abortion Outbreaks in Italian Pig Farms from 2011 to 2021

Veterinary Sciences
The present study retrospectively analyzed the infectious agents associated with 829 abortion outbreaks occurring from 2011 to 2021 in northern Italy. Foetuses were subjected to necropsies, and organ samples were analyzed by direct PCR to screen for six ...
Anna Donneschi, Matteo Recchia, Claudia Romeo, Paolo Pozzi, Cristian Salogni, Antonio Marco Maisano, Giovanni Santucci, Federico Scali, Silvia Faccini, Maria Beatrice Boniotti, Mario D’Incau, Dominiek Maes, Giovanni Loris Alborali   +12 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Protective effects of saffron against zearalenone-induced alterations in reproductive hormones in female mice (Mus musculus). [PDF]

, 2018
OBJECTIVE: Zearalenone (ZEA) is a mycotoxin with potent estrogenic effects. Saffron is an herbal product that has antioxidant activities. The objective of this study was to investigate the protective role of saffron against reproductive toxicity induced ...
Saleh, Ramadan, Agarwal, Ashok, Shrivastava, Vinoy K, Ahmad, Bashir, Henkel, Ralf   +4 more
core   +1 more source

The Fate of Leydig Cells in Men with Spermatogenic Failure

, 2022
The steroidogenic cells in the testicle, Leydig cells, located in the interstitial compartment, play a vital role in male reproductive tract development, maintenance of proper spermatogenesis, and overall male reproductive function.
Renata Walczak-Jędrzejowska, Daria Adamczewska, Jolanta Słowikowska-Hilczer   +2 more
core   +1 more source

Evaluation of IgM, IgA, and IgG Antibody Responses Against PCV3 and PCV2 in Tissues of Aborted Fetuses from Late-Term Co-Infected Sows

Pathogens
Porcine circovirus type 2 (PCV2) is a ubiquitous pathogen, and co-infections with the emerging PCV3 are increasingly reported. Both PCV2 and PCV3 have been implicated in reproductive failure, yet the diagnostic criteria for PCV3 remain under development.
Jesús Hernández, Alexandra Henao-Díaz, Mónica Reséndiz-Sandoval, Joana Ramírez-Morán, Angel Cota-Valdez, Verónica Mata-Haro, Luis G. Giménez-Lirola   +6 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source