Results 131 to 140 of about 1,046,081 (384)

Associations of prenatal co-exposure to phthalate metabolites and bisphenols with neural tube defects

open access: yesEnvironmental Sciences Europe
Introduction Neural tube defects (NTDs) are one of the most common birth defects. Phthalates and bisphenols are ubiquitous endocrine-disrupting chemicals (EDCs), which can disrupt the endocrine system by altering hormone levels.
Sainan Li   +9 more
doaj   +1 more source

Targeting rapid TKI‐induced AXL upregulation overcomes adaptive ERK reactivation and exerts antileukemic effects in FLT3/ITD acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
Adaptive ERK reactivation hinders FLT3 tyrosine kinase inhibitor (TKI) treatment in FLT3/ITD acute myeloid leukemia. Here, we report that FLT3 TKI treatment rapidly induces AXL expression and upregulation that is temporally associated with the adaptive ERK reactivation.
Tessa S. Seale   +9 more
wiley   +1 more source

Health Promotion Model "Extracurricular" Approach of Reproductive Health Among Early Adolescents [PDF]

open access: yes, 2018
The behavior to maintenance of reproductive organs, and self-adjustment on changes during puberty become its own problems on early adolescence (10-14 years old).
Hastuti, L. (Lidia)   +4 more
core  

Combined spatially resolved metabolomics and spatial transcriptomics reveal the mechanism of RACK1‐mediated fatty acid synthesis

open access: yesMolecular Oncology, EarlyView.
The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu   +3 more
wiley   +1 more source

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

open access: yesMolecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld   +7 more
wiley   +1 more source

Self-similarity in pandemic spread and fractal containment policies [PDF]

open access: yesarXiv
Although pandemics are often studied as if populations are well-mixed, disease transmission networks exhibit a multi-scale structure stretching from the individual all the way up to the entire globe. The COVID-19 pandemic has led to an intense debate about whether interventions should prioritize public health or the economy, leading to a surge of ...
arxiv  

Adolescent Male Reproductive Health Knowledge and Practices in Bangladesh

open access: hybrid, 1970
Faez Ahmed   +3 more
openalex   +2 more sources

Integrative systems‐level analysis reveals a contextual crosstalk between hypoxia and global metabolism in human breast tumors

open access: yesMolecular Oncology, EarlyView.
Breast tumor samples scored for metabolic deregulation (M1 to M3) were given a hypoxia score (HS). The highest HS occurred in patients with strongest metabolic deregulation (M3), supporting tumor aggressiveness. HS correlated with the highest number of metabolic pathways in M1. This suggests hypoxia to be an early event in metabolic deregulation.
Raefa Abou Khouzam   +2 more
wiley   +1 more source

Gender and Reproductive Health [PDF]

open access: yes, 2001
Smelser, Neil J. [Hrsg.]   +1 more
openaire   +2 more sources

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