Results 131 to 140 of about 668,258 (314)

Exploration of the dynamic regulation of the hypothalamic-pituitary-ovarian axis during the estrous cycle

Journal of Ovarian Research
Background One of the most challenging issues in current assisted reproductive technology is how to optimally counsel and treat patients with poor ovarian response (POR). However, current research predominantly emphasized the ovarian local changes during
Jian Sun, Minghui Lu, Chaoyan Yang, Yixiao Cheng, Peiwen Xu, Rusong Zhao, Yuan Gao   +6 more
doaj   +1 more source

The pyruvate generator is a common phenomenon in mitochondria from different rat and mouse brain regions

FEBS Letters, EarlyView.
The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber, Niki Karavasili, Matthias Kunz, Zemfira Gizatullina, Timur Gainutdinov, Stefan Vielhaber, Wolfram S. Kunz, Frank N. Gellerich   +7 more
wiley   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

The impact of pre-pregnancy overweight/obesity on the birth weight of offspring born from women with polycystic ovarian syndrome

BMC Pregnancy and Childbirth
Objectives The purpose of our study is to explore whether polycystic ovary syndrome (PCOS) has an independent impact on the neonatal birth weight (BW), and whether pre-pregnancy overweight/obesity plays a mediating role on the association between PCOS ...
Jiejing Jiao, Yiyuan Zhang, Jiayi Zhou, Rui Lv, Linlin Cui   +4 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Knowledge Summary 20: Access to Family Planning [PDF]

, 2012
Ensuring universal access to reproductive health and rights, including family planning, is key to achieving global goals to improve women’s and children’s health.
Partnership for Maternal, Newborn and Child Health
core  

Kenya: Communities support adolescent reproductive health education

, 2003
Young people in Kenya have limited knowledge of reproductive health (RH) and face many challenges in their transition to adulthood. Chief among these challenges is the high prevalence of HIV/AIDS among adults and its increasing incidence among rural ...
Frontiers in Reproductive Health
core   +1 more source

Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila

FEBS Letters, EarlyView.
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia, Anna Dósa, Asha Kiran Maddali, András Jipa, Hajnalka Laczkó‐Dobos, Péter Lőw, Gábor Juhász   +6 more
wiley   +1 more source

Mothers and sisters: educators of sexual health information among young Niue women born in New Zealand

, 2019
Background: For many Pacific youth in New Zealand, discussing sexual health topics with their parents or families remains a highly sensitive subject that is uncomfortable and culturally challenging.
Nosa, Vili, Ikihele, Amio
core   +1 more source

The threshold of estradiol level for fresh embryo transfer differs between blastocyst and cleavage‐stage embryo

Acta Obstetricia et Gynecologica Scandinavica
Introduction Ovarian stimulation can cause supraphysiological estradiol levels and adverse effects on endometrial receptivity. Since patients could undergo cleavage or blastocyst stage embryo transfer, the threshold value of peak estradiol level for each
Dingying Zhao, Huiying Xiao, Gege Ouyang, Yuan Fang, Qiaoqiao Ding, Yue Niu, Jialin Zou, Yanran Liu, Xue Shang, Ze Wang, Zi‐Jiang Chen, Lianlian Liu, Daimin Wei   +12 more
doaj   +1 more source