Results 61 to 70 of about 668,258 (314)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Reproductive Health and Reproductive Vulnerability

open access: yesEtnoantropološki Problemi, 2016
Reproductive health represents, almost to an equal extent, a socio-cultural and a medical fact. What influences it, both positively and negatively, stems from the ways in which we culturally cognize and act with regard to reproductive behavior.
Bojan Žikić
doaj  

Clients’ expectations and experiences with providers of menstrual regulation: a qualitative study in Bangladesh

open access: yesBMC Women's Health
Background Menstrual Regulation (MR) has been legal in Bangladesh since 1979 in an effort to reduce maternal mortality from unsafe abortion care. However, access to high-quality and patient-centered MR care remains a challenge.
Ana Maria Ramirez   +6 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Reproductive Health

open access: yes, 2002
Reproductive health (RH) problems account for a significant part of the burden of disease suffered by poor people in developing countries. Poor women and men are more afflicted with RH problems and often lack
World Bank
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Youth reproductive health: Investing in the future

open access: yes, 2009
Youth—young people aged 10–24—constitute about a quarter of the world\u27s population. Nearly three-quarters of these young people live in the developing world, and they suffer a disproportionate share of unplanned pregnancies, STIs including HIV, and ...
Frontiers in Reproductive Health
core   +1 more source

Process of couple communication in reproductive health among rural married couples in India [PDF]

open access: yes, 2009
Communication is often recognized as a cornerstone of modern society. Helping couples communicate about reproductive health is viewed as vital for involvement of both the partners in decision making, treatment seeking and promoting health.
Santosh Karvande, Shilpa
core   +1 more source

Population-level analyses identify host and environmental variables influencing the vaginal microbiome

open access: yesSignal Transduction and Targeted Therapy
The vaginal microbiome is critical for the reproductive health of women, yet the differential impacts exerted by the host and by ambient environmental variables on the vaginal microbiome remain largely unknown.
Lang Qin   +35 more
doaj   +1 more source

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