Results 111 to 120 of about 147,088 (237)

Reproductive isolation at contact zones

, 2021
Speciation is among the most important evolutionary processes that contribute to biodiversity. It involves the formation of new species that have become reproductively isolated through a process that is not linear and varies in time and space. For divergent populations that still exchange genes, questions remain on how selective forces and demographic ...
openaire  

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Strong postmating reproductive isolation in Mimulus section Eunanus. [PDF]

J Evol Biol, 2023
Farnitano MC, Sweigart AL.
europepmc   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

A toxin-antidote system contributes to interspecific reproductive isolation in rice. [PDF]

Nat Commun, 2023
You S, Zhao Z, Yu X, Zhu S, Wang J, Lei D, Zhou J, Li J, Chen H, Xiao Y, Chen W, Wang Q, Lu J, Chen K, Zhou C, Zhang X, Cheng Z, Guo X, Ren Y, Zheng X, Liu S, Liu X, Tian Y, Jiang L, Tao D, Wu C, Wan J.   +26 more
europepmc   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Reproductive isolation, speciation, and the value of disagreement: A reply to the commentaries on 'What is reproductive isolation?' [PDF]

J Evol Biol, 2022
Westram AM, Stankowski S, Surendranadh P, Barton NH.   +3 more
europepmc   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Constructing sympatry networks to assess potential introgression pathways within the major oak sections in the contiguous US states

Plants, People, Planet
Societal Impact Statement Increasing evidence indicates gene flow commonly occurs between closely related species in diverse plant genera and can involve numerous species.
Charles H. Cannon, John Kartesz, Sean Hoban, M. Isabel Loza, Emily Beckman Bruns, Andrew L. Hipp   +5 more
doaj   +1 more source

Editorial: Molecular insights in plant reproductive isolation barriers. [PDF]

Front Plant Sci, 2023
Mino M, Lafon Placette C, Tezuka T.
europepmc   +1 more source