Results 101 to 110 of about 387,167 (258)

Ecological diversification in sexual and asexual lineages

Scientific Reports
The presence or absence of sex can have a strong influence on the processes whereby species arise. Yet, the mechanistic underpinnings of this influence are poorly understood.
P. Catalina Chaparro-Pedraza, Gregory Roth, Carlos J. Melián   +2 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Binary or Nonbinary Fission? Reproductive Mode of a Predatory Bacterium Depends on Prey Size. [PDF]

mBio, 2023
Pląskowska K, Makowski Ł, Strzałka A, Zakrzewska-Czerwińska J.   +3 more
europepmc   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Contrasting Evolutionary Patterns Between Sexual and Asexual Lineages in a Genomic Region Linked to Reproductive Mode Variation in the pea aphid. [PDF]

Genome Biol Evol, 2023
Rimbault M, Legeai F, Peccoud J, Mieuzet L, Call E, Nouhaud P, Defendini H, Mahéo F, Marande W, Théron N, Tagu D, Le Trionnaire G, Simon JC, Jaquiéry J.   +13 more
europepmc   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Variation in reproductive mode across the latitudinal range of invasive Russian knapweed. [PDF]

AoB Plants, 2022
Gaskin JF, Littlefield JL, Rand TA, West NM.   +3 more
europepmc   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Bidirectional Mendelian randomization to explore the causal relationships between the gut microbiota and male reproductive diseases

Scientific Reports
Gut bacteria might play an important role in male reproductive disorders, such as male infertility and sperm abnormalities; however, their causal role is unclear.
Xiaofang Han, Hui Tian, Liu Yang, Yuanyuan Ji   +3 more
doaj   +1 more source

Observations of biennial reproduction in Caribbean reef sharks ‘Carcharhinus perezi’

Frontiers in Marine Science
Effective management and conservation of threatened species biodiversity requires knowledge of reproductive biology, such as cyclicity, mode, and age at maturity.
Beckah A. Campbell, Oliver N. Shipley, Taeler R. Jones, Austin J. Gallagher, James A. Sulikowski   +4 more
doaj   +1 more source