Results 101 to 110 of about 2,854,940 (249)

Law, Rights and Reproduction: Reproductive Autonomy in Ethical Rationalism [PDF]

open access: yes, 2016
As medical technology has advanced, so too have our attitudes towards the level of control we can expect to hold over our procreative capacities. This creates a multi-dimensional problem for the law in terms of access to services which prevent conception,
Clayton Thompson, J.
core   +1 more source

Accountability for Sexual and Reproductive Health and Rights in Humanitarian and Disaster Situations: Case Studies from Uganda, Bangladesh, and Nepal [PDF]

open access: yesHealth and Human Rights
Sexual and reproductive health and rights (SRHR) during conflicts and disasters are protected under multiple legal and policy frameworks; however, weak accountability mechanisms often prevent these rights from being realized. Drawing on case studies from
Grady Arnott   +4 more
doaj  

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

Comparing the paths of Hedgehog release in artificial and natural settings

open access: yesFEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

Rights and responsibilities: consultation report [PDF]

open access: yes, 2015
Rights & Responsibilities 2014 was a national consultation conducted by the Human Rights Commissioner between August and December 2014. The consultation examined how well people think their human rights and freedoms are protected in Australia ...
Australian Human Rights Commission
core  

A commentary on the recent ruling by the Thai Constitutional Court in relation to abortion law in Thailand

open access: yesSexual and Reproductive Health Matters, 2020
K. Chaturachinda, N. Boonthai
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Abortion, reproductive rights and maternal mortality

open access: yes, 1994
The authors make their case for safe, legal, accessible, affordable abortion, as one part of reproductive health services that make all the choices, and information, available to women.
Sweetman, Caroline   +3 more
core   +1 more source

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