Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
The Rule of Law for the Exercise of Marriage and Reproductive Rights for Women with Intellectual Disabilities in China. [PDF]
Risk Manag Healthc Policy, 2022 Huang Z, Chen B, Feng Z.
europepmc +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Knowledge and Awareness of Reproductive Rights Among Women With Schizophrenia and Bipolar Affective Disorder. [PDF]
CureusMajhi G, Lingam P, M N V, A U S.
europepmc +1 more source
Debilitated Lifeworlds: Women's Narratives of Forced Sterilization as Delinking from Reproductive Rights. [PDF]
Med Anthropol Q, 2022 Chaparro-Buitrago J.
europepmc +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
A sexual and reproductive health and rights journey: from Cairo to the present
Sexual and Reproductive Health Matters, 2019 Rebecca Brown +6 more
doaj +1 more source
The Double Dominion Over Women's Bodies as a barrier to exercising sexual and reproductive rights: a mixed-methods study in La Ladrillera, Mexico. [PDF]
Lancet Reg Health AmBejarano Zambrano CL +6 more
europepmc +1 more source
'The law is very, very outdated and not keeping up with the technology': novel forms of assisted gestation, legal challenges, and perspectives of reproductive rights advocates in England and Wales. [PDF]
J Law Biosci, 2023 Romanis EC.
europepmc +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source