Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Infertility and reproductive rights after the COVID-19 pandemic. [PDF]
Reprod Biomed Online, 2020 Trinchant RM +3 more
europepmc +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Healthcare providers' perceptions of immigrant patients' values about sexual and reproductive rights: a cross-sectional comparison with immigrants' self-reported values. [PDF]
Reprod HealthTibajev A +3 more
europepmc +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
FemTech: empowering reproductive rights or FEM-TRAP for surveillance? [PDF]
Med Law RevHofmann D.
europepmc +1 more source
Preserving the Reproductive Rights of Girls and Women in the Era of COVID-19: The Need for a Least Restrictive Solution. [PDF]
Am J Bioeth, 2020 Ott MA, Bernard C.
europepmc +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Revisiting restricted reproductive rights in 2025: what do we need to know now? [PDF]
Antimicrob Steward Healthc EpidemiolBailey P +3 more
europepmc +1 more source
Operationalising human rights for sexual and reproductive health: celebrations, achievements and challenges [PDF]
, 2008 Lindsay Edouard
openalex +1 more source