Results 31 to 40 of about 386,943 (302)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

The MacArthur Foundation in Nigeria: Report on Activities 2009 [PDF]

open access: yes, 2009
Highlights the foundation's work to build the scientific research capacity of Nigerian universities, to reduce maternal mortality and improve sexual and reproductive health, and to advance human rights.

core  

The Polish Parliament and the making of politics through abortion : nation, gender and democracy in the 1996 Liberalization Amendment Debate [PDF]

open access: yes, 2009
The collapse of communism across East Central Europe was marked by a renewal of debates around reproduction, with abortion debates surfacing in Romania, Germany and Poland.
Kramer, Anne-Marie Caroline
core   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Fulfillment of Maternal Health As Part of Human Rights: A Case Study of Banyuwangi Municipality of East Java, Indonesia [PDF]

open access: yes, 2011
This article is result of research on the fulfillment of maternal health which conducted in one of city in East Java Indonesia. Approach used for this research is human rights based which also utilise 3-A and 1-Q elements (availability, accessibility ...
Christanti, Inge   +2 more
core  

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

Population and Reproductive Health [PDF]

open access: yes, 2009
Outlines the foundation's grantmaking strategies to reduce maternal mortality and morbidity and to advance youths' sexual and reproductive health and rights.

core  

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Refusing disembodiment: abortion and the paradox of reproductive rights in contemporary Italy [PDF]

open access: yes, 2009
Employing insights from Italian sexual difference theory on law and rights, this article examines how both the text of the Italian Abortion Law of 1978 and its operation reveal the contradictions within liberal rights discourse on reproductive freedom ...
Hanafin, Patrick
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

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