Results 41 to 50 of about 391,028 (345)

Why Family Planning and Reproductive Health are Critical to the Well-Being of Youth [PDF]

open access: yes, 2009
An unprecedented number of young people are entering their reproductive years, most of whom live in the developing world. U.S. policy makers should assist in effortS to ensure that youth worldwide are able to make informed decisions about their sexuality

core  

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Globalization, Health Sector Reform, Gender and Reproductive Health [PDF]

open access: yes, 2001
Explores the interrelationships between globalization and health sector reforms, and how changes in macro-economic and social policies affect women's reproductive health and ...
Barbara Evers   +5 more
core  

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

Fulfillment of Maternal Health As Part of Human Rights: A Case Study of Banyuwangi Municipality of East Java, Indonesia [PDF]

open access: yes, 2011
This article is result of research on the fulfillment of maternal health which conducted in one of city in East Java Indonesia. Approach used for this research is human rights based which also utilise 3-A and 1-Q elements (availability, accessibility ...
Christanti, Inge   +2 more
core  

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Sexual violence among adolescent girls and young women in Malawi: a cluster-randomized controlled implementation trial of empowerment self-defense training

open access: yesBMC Public Health, 2018
Background Globally, sexual violence is prevalent, particularly for adolescent women. This cluster-randomized controlled implementation trial examines empowerment self-defense (ESD) for sexual assault risk reduction among school-age women in Malawi ...
Michele R. Decker   +8 more
doaj   +1 more source

Grantmaking in Mexico [PDF]

open access: yes, 2010
Provides an updated summary of the foundation's grantmaking in Mexico since 1986 in the areas of human rights, population and reproductive health, and migration issues.

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Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

The MacArthur Foundation in Nigeria: Report on Activities 2009 [PDF]

open access: yes, 2009
Highlights the foundation's work to build the scientific research capacity of Nigerian universities, to reduce maternal mortality and improve sexual and reproductive health, and to advance human rights.

core  

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