Results 71 to 80 of about 391,028 (345)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Perlindungan Hukum Terhadap Tenaga Kerja Wanita Terkait Hak Reproduksi Di Kota Manado

open access: yesJurnal Nuansa Akademik
This study aims to examine the protection of female workers related to reproductive rights. Women's reproductive rights are when they menstruate, become pregnant (pregnancy), give birth, and postpartum and certain conditions experienced by women.
Jolanda M. Korua   +5 more
doaj   +1 more source

Mapping adolescent sexual and reproductive health research in sub-Saharan Africa: protocol for a scoping review

open access: yesBMJ Open, 2020
Introduction Previous studies have attempted to review the vast body of evidence on adolescent sexual and reproductive health (ASRH), but none has focused on a complete mapping and synthesis of the body of inquiry and evidence on ASRH in sub-Saharan ...
Anthony Idowu Ajayi   +6 more
doaj   +1 more source

Bioethics bonanza [PDF]

open access: yes, 1999
Over the past couple of years, the Bioethics Consultative Committee has been active in promoting an understanding of bioethical issues within the medical profession, as well as more generally among the paramedical, and indeed the lay public.
Cauchi, Maurice N.
core  

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Legal Form, Commodities and Reproduction: Reading Pashukanis [PDF]

open access: yes, 2013
This chapter offers a feminist reading of Pashukanis’s legal theory as a contribution to critical evaluation of the relationship between legality, commodification and gender. Contemporary feminist interests in the relationship between legal and non-legal
FLETCHER, R
core  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

The Women’s Convention, Reproductive Rights, and the Reproduction of Gender [PDF]

open access: yes, 2011
The 2011 symposium: The Changing Face of Families, will focus on the evolution of assisted reproductive technologies, and its effects on traditional legal notions of marriage, parent, and ...
Stark, Barbara
core   +3 more sources

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